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- Validation of a novel non-invasive high throughput screening tool for peripheral neuropathy in type 2 diabetes
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Research & impact
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Research groups
- Retinal Disease and Clinical Imaging Research Group
- Optical Imaging and Visualisation
- Public Health and Health Systems Research Group
- Myopia Research Group
- Ocular Surface Research (Inc. Dry Eye and Contact Lenses)
- Centre for Eye Health Research Group (CFEH)
- Sensory Processes Research Laboratory
- Eye Research Group
- Vision Loss and Health Ageing Group
- Testing and developing new antimicrobials and overcoming antimicrobial resistance (TADOAR)
- Ocular Pathology Research Group
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Research excellence
- Validation of a novel non-invasive high throughput screening tool for peripheral neuropathy in type 2 diabetes
- Eye infection and contact lens
- Development of novel antimicrobial scaffolds
- Preventing injuries and promoting health, safety and mobility for older people with age-related eye disease
- Biomarkers in dry eye disease
- Publications
- Volunteer in our research studies
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Research groups
- Partner with us
- Optometry clinic
- ORLAB
- About us
- Study areas
- Student life & resources
-
Research & impact
Research groups
- Retinal Disease and Clinical Imaging Research Group
- Optical Imaging and Visualisation
- Public Health and Health Systems Research Group
- Myopia Research Group
- Ocular Surface Research (Inc. Dry Eye and Contact Lenses)
- Centre for Eye Health Research Group (CFEH)
- Sensory Processes Research Laboratory
- Eye Research Group
- Vision Loss and Health Ageing Group
- Testing and developing new antimicrobials and overcoming antimicrobial resistance (TADOAR)
- Ocular Pathology Research Group
Research excellence
- Validation of a novel non-invasive high throughput screening tool for peripheral neuropathy in type 2 diabetes
- Eye infection and contact lens
- Development of novel antimicrobial scaffolds
- Preventing injuries and promoting health, safety and mobility for older people with age-related eye disease
- Biomarkers in dry eye disease
- Partner with us
- Optometry clinic
- ORLAB
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There is an unmet medical need for early diagnosis and monitoring of diabetic neuropathy, particularly in remote locations that do not have access to specialty care. Using the eye to monitor tear neuropeptides may allow early diagnosis and prevent complications.
Competitive advantage
In type 1 diabetes, measuring the release of tear film neuropeptides, specifically substance P, from corneal nerve terminals may allow us to diagnose diabetic peripheral neuropathy. It is planned to determine if this also applies to type 2 diabetes.
Impact
Patients with type 2 diabetes and neuropathy are more likely to suffer from pain, foot ulceration and mortality. It may be possible to limit the progression of neuropathy and more severe consequences by identifying the conditions early and reducing risk factors more aggressively.
Successful outcomes
This project will translate the development of point-of-care assessment technique to assess the presence of diabetic peripheral neuropathy. It would involve developing an instrument that can be used by non-specialists in remote communities and allow for referral based on a positive outcome.
Capabilities and facilities
This work is part of a collaborative effort between the School of Optometry & Vision Science, the Prince of Wales Diabetes and Endocrinology Centre and the Prince of Wales Medical School.
Our partners
- The Prince of Wales Diabetes and Endocrinology Centre
- The Prince of Wales Medical School
More information
Maria Markoulli
Associate Professor and Postgraduate Research Coordinator
UNSW School of Optometry & Vision Science
+612 9065 735
m.markoulli@unsw.edu.au, opens in a new window