Po JW; Ma Y; Balakrishnar B; Brungs D; Azimi F; Cooper A; Saricilar E; Murthy V; de Souza P; Becker TM, 2021, 'PD-L1 Detection on Circulating Melanoma Cells', in Melanoma: Methods and Protocols, pp. 223 - 233, http://dx.doi.org/10.1007/978-1-0716-1205-7_17
Book Chapters | 2021
Po JW; Ma Y; Luk AWS; Lynch D; Balakrishnar B; Brungs D; Azimi F; Cooper A; Saricilar E; Murthy V; de Souza P; Becker TM, 2021, 'Single-Cell Analysis of BRAFV600E and NRASQ61R Mutation Status in Melanoma Cell Lines as Method Generation for Circulating Melanoma Cells', in Melanoma: Methods and Protocols, pp. 277 - 286, http://dx.doi.org/10.1007/978-1-0716-1205-7_21
Book Chapters | 2016
Po JW; Lynch D; de Souza P; Becker TM, 2016, 'Importance and Detection of Epithelial-to-Mesenchymal Transition (EMT) Phenotype in CTCs', in Xu K(ed.), TUMOR METASTASIS, INTECH EUROPE, pp. 241 - 256, http://dx.doi.org/10.5772/64342
Book Chapters | 2013
Becker T; Haferkamp S, 2013, 'Molecular Mechanisms of Cellular Senescence', in Senescence and Senescence-Related Disorders, InTech, http://dx.doi.org/10.5772/54120
Book Chapters | 2003
Becker TM; Rizos H, 2003, 'Regulation of Cellular Senescence by the Retinoblastoma Pathway', in Aging of Cells in and Outside the Body, Springer Netherlands, pp. 151 - 169, http://dx.doi.org/10.1007/978-94-017-0669-8_9
Book Chapters | 2003
Rizos H; Becker T; Holland E, 2003, 'Cell cycle regulation in the melanocyte', in Textbook of Melanoma, CRC Press, pp. 13 - 24, http://dx.doi.org/10.1201/b14732-3
Journal articles | 2024
Chan WY; Chua W; Wilkinson K; Epitakaduwa C; Mandaliya H; Descallar J; Roberts TL; Becker TM; Ng W; Lee CS; Lim SHS, 2024, 'The Prognostic and Predictive Utility of CDX2 in Colorectal Cancer', International Journal of Molecular Sciences, 25, http://dx.doi.org/10.3390/ijms25168673
Journal articles | 2024
El-Kamand S; Quinn JMW; Sareen H; Becker TM; Wong-Erasmus M; Cowley MJ, 2024, 'CRUX, a platform for visualising, exploring and analysing cancer genome cohort data', NAR Genomics and Bioinformatics, 6, http://dx.doi.org/10.1093/nargab/lqae003
Journal articles | 2024
Hirani R; Ross B; Ma Y; Irish K; Chamberlain J; Becker T; Smalley A; Irving H; Irving DO, 2024, 'The incidence of donor white blood cell survival (transfusion-associated microchimerism) in Australian pediatric patients', Transfusion, 64, pp. 1830 - 1840, http://dx.doi.org/10.1111/trf.18010
Journal articles | 2024
Ho V; Chung L; Wilkinson K; Ma Y; Rutland T; Lea V; Lim SH; Abubakar A; Ng W; Lee M; Roberts TL; Becker TM; Mackenzie S; Chua W; Lee CS, 2024, 'Microsatellite Instability Testing and Prognostic Implications in Colorectal Cancer', Cancers, 16, http://dx.doi.org/10.3390/cancers16112005
Journal articles | 2024
Lea V; Lim SH-S; Chua W; Ng WL; Wang B; Wilkinson KJ; Farzin M; Habashy P; Roberts T; Becker T; Lee CS, 2024, 'Incidence and potential prognostic implications of fibroblast growth factor receptor gene alterations and coexisting mutations in colorectal cancer.', Journal of Clinical Oncology, 42, pp. e15558 - e15558, http://dx.doi.org/10.1200/jco.2024.42.16_suppl.e15558
Journal articles | 2024
Lock JG; Mann TJ; Zheng Y; Khan T; Neumann D; James A; Becker T; Roberts T, 2024, 'Abstract A031: Harnessing the potential of circulating tumour cells for precision diagnostics via multiplexed imaging of the levels and subcellular localizations of over 50 cell identity, state and signaling markers per cell', Clinical Cancer Research, 30, pp. A031 - A031, http://dx.doi.org/10.1158/1557-3265.liqbiop24-a031
Journal articles | 2024
Nindra U; Lin P; Becker T; Roberts TL; Chua W, 2024, 'Current state of theranostics in metastatic castrate-resistant prostate cancer', Journal of Medical Imaging and Radiation Oncology, 68, pp. 412 - 420, http://dx.doi.org/10.1111/1754-9485.13658
Journal articles | 2024
Nindra U; Pal A; Bray V; Yip PY; Tognela A; Roberts TL; Becker TM; Williamson J; Farzin M; Li JJ; Lea V; Hagelamin A; Ng W; Wang B; Lee CS; Chua W, 2024, 'Utility of multigene panel next-generation sequencing in routine clinical practice for identifying genomic alterations in newly diagnosed metastatic nonsmall cell lung cancer', Internal Medicine Journal, 54, pp. 596 - 601, http://dx.doi.org/10.1111/imj.16224
Journal articles | 2023
Davoudi F; Moradi A; Becker TM; Lock JG; Abbey B; Fontanarosa D; Haworth A; Clements J; Ecker RC; Batra J, 2023, 'Genomic and Phenotypic Biomarkers for Precision Medicine Guidance in Advanced Prostate Cancer', Current Treatment Options in Oncology, 24, pp. 1451 - 1471, http://dx.doi.org/10.1007/s11864-023-01121-z
Journal articles | 2023
Grebstad Tune B; Sareen H; Powter B; Kahana-Edwin S; Cooper A; Koh ES; Lee CS; Po JW; McCowage G; Dexter M; Cain L; O’Neill G; Prior V; Karpelowsky J; Tsoli M; Baumbusch LO; Ziegler D; Roberts TL; DeSouza P; Becker TM; Ma Y, 2023, 'From Pediatric to Adult Brain Cancer: Exploring Histone H3 Mutations in Australian Brain Cancer Patients', Biomedicines, 11, http://dx.doi.org/10.3390/biomedicines11112907
Journal articles | 2023
Habashy P; Lea V; Wilkinson K; Wang B; Wu XJ; Roberts TL; Ng W; Rutland T; Po JW; Becker T; Descallar J; Lee M; Mackenzie S; Gupta R; Cooper W; Lim S; Chua W; Lee CS, 2023, 'KRAS and BRAF Mutation Rates and Survival Outcomes in Colorectal Cancer in an Ethnically Diverse Patient Cohort', International Journal of Molecular Sciences, 24, http://dx.doi.org/10.3390/ijms242417509
Journal articles | 2023
Marivel AMJ; Ma Y; Becker TM; Verma A; Trieu S; Roberts TL; Ling SCW, 2023, 'The use of cell free DNA (cfDNA) for mutational screening of multiple myeloma', Leukemia Research Reports, 20, pp. 100393, http://dx.doi.org/10.1016/j.lrr.2023.100393
Journal articles | 2023
Nindra U; Pal A; Lea V; Lim SHS; Wilkinson K; Asghari R; Roberts TL; Becker TM; Farzin M; Rutland T; Lee M; MacKenzie S; Ng W; Wang B; Soon Lee C; Chua W, 2023, 'Multigene panel next generation sequencing in metastatic colorectal cancer in an Australian population', PLoS ONE, 18, http://dx.doi.org/10.1371/journal.pone.0292087
Journal articles | 2022
, 2022, 'Towards Diagnostic ctDNA Testing in Multiple Myeloma: How does Automated Magnetic Bead-Based Cell-Free DNA Extraction Compare to the Leading Silica Membrane-Based Manual Extraction?', Biomarkers and Applications, 5, http://dx.doi.org/10.29011/2576-9588.100043
Journal articles | 2022
Fatima S; Ma Y; Safrachi A; Haider S; Spring KJ; Vafaee F; Scott KF; Roberts TL; Becker TM; de Souza P, 2022, 'Harnessing Liquid Biopsies to Guide Immune Checkpoint Inhibitor Therapy', Cancers, 14, http://dx.doi.org/10.3390/cancers14071669
Journal articles | 2022
Jeffreys SA; Becker TM; Khan S; Soon P; Neubauer H; de Souza P; Powter B, 2022, 'Prognostic and Predictive Value of CCND1/Cyclin D1 Amplification in Breast Cancer With a Focus on Postmenopausal Patients: A Systematic Review and Meta-Analysis', Frontiers in Endocrinology, 13, http://dx.doi.org/10.3389/fendo.2022.895729
Journal articles | 2022
Khan T; Becker TM; Po JW; Chua W; Ma Y, 2022, 'Single-Circulating Tumor Cell Whole Genome Amplification to Unravel Cancer Heterogeneity and Actionable Biomarkers', International Journal of Molecular Sciences, 23, http://dx.doi.org/10.3390/ijms23158386
Journal articles | 2022
Khan T; Becker TM; Scott KF; Descallar J; de Souza P; Chua W; Ma Y, 2022, 'Prognostic and Predictive Value of Liquid Biopsy-Derived Androgen Receptor Variant 7 (AR-V7) in Prostate Cancer: A Systematic Review and Meta-Analysis', Frontiers in Oncology, 12, http://dx.doi.org/10.3389/fonc.2022.868031
Journal articles | 2022
Khan T; Lock JG; Ma Y; Harman DG; de Souza P; Chua W; Balakrishnar B; Scott KF; Becker TM, 2022, 'Choice of antibody is critical for specific and sensitive detection of androgen receptor splice variant-7 in circulating tumor cells', Scientific Reports, 12, http://dx.doi.org/10.1038/s41598-022-20079-w
Journal articles | 2022
Pai K; Buckley NA; Isoardi KZ; Isbister GK; Becker T; Chiew AL; Cairns R; Brown JA; Chan BS, 2022, 'Optimising alkalinisation and its effect on QRS narrowing in tricyclic antidepressant poisoning', British Journal of Clinical Pharmacology, 88, pp. 723 - 733, http://dx.doi.org/10.1111/bcp.15008
Journal articles | 2022
Sareen H; Ma Y; Becker TM; Roberts TL; de Souza P; Powter B, 2022, 'Molecular Biomarkers in Glioblastoma: A Systematic Review and Meta-Analysis', International journal of molecular sciences, 23, http://dx.doi.org/10.3390/ijms23168835
Journal articles | 2022
Tincknell G; Naveed A; Nankervis J; Mukhtiar A; Piper AK; Becker TM; Chantrill L; Aghmesheh M; Vine KL; Ranson M; Brungs D, 2022, 'HER2-Positive Gastroesophageal Cancers Are Associated with a Higher Risk of Brain Metastasis', Cancers, 14, http://dx.doi.org/10.3390/cancers14235754
Journal articles | 2022
Woodford R; Brungs D; Leighton C; Grimison P; Sjoquist KM; Becker T; Robinson S; Gebski V; Wilson K; Chantrill L; Aghmesheh M, 2022, 'Combination chemotherapy with NAB®-paclitaxel and capecitabine for patients with advanced biliary tract cancer (NAP-CAPABIL Pilot Study)', Asia-Pacific Journal of Clinical Oncology, 18, pp. e220 - e226, http://dx.doi.org/10.1111/ajco.13599
Journal articles | 2022
Yeap I; Becker T; Azimi F; Kernohan M, 2022, 'The management of hereditary melanoma, FAMMM syndrome and germline CDKN2A mutations: a narrative review', Australasian Journal of Plastic Surgery, 5, pp. 12 - 22, http://dx.doi.org/10.34239/ajops.v5n2.324
Journal articles | 2022
Young FP; Becker TM; Nimir M; Opperman T; Chua W; Balakrishnar B; de Souza P; Ma Y, 2022, 'Biomarkers of Castrate Resistance in Prostate Cancer: Androgen Receptor Amplification and T877A Mutation Detection by Multiplex Droplet Digital PCR', Journal of Clinical Medicine, 11, http://dx.doi.org/10.3390/jcm11010257
Journal articles | 2021
Adam T; Becker TM; Chua W; Bray V; Roberts TL, 2021, 'The multiple potential biomarkers for predicting immunotherapy response-finding the needle in the haystack', Cancers, 13, pp. 1 - 20, http://dx.doi.org/10.3390/cancers13020277
Journal articles | 2021
Ding PN; Roberts TL; Chua W; Becker TM; Caixeiro N; de Souza P; Gao B; Lee CK; Itchins M; Westman H; Clarke S; Blinman P; Kao S; John T; Leal JL; Bray VJ, 2021, 'Plasma pre-treatment T790M relative allelic frequency in patients with advanced EGFR-mutated non-small cell lung cancer predicts treatment response to subsequent-line osimertinib', Translational Lung Cancer Research, 10, pp. 1623 - 1634, http://dx.doi.org/10.21037/tlcr-20-1125
Journal articles | 2021
Garrett C; Becker TM; Lynch D; Po J; Xuan W; Scott KF; De Souza P, 2021, 'Comparison of neutrophil to lymphocyte ratio and prognostic nutritional index with other clinical and molecular biomarkers for prediction of glioblastoma multiforme outcome', PLoS ONE, 16, http://dx.doi.org/10.1371/journal.pone.0252614
Journal articles | 2021
Pang TCY; Po JW; Becker TM; Goldstein D; Pirola RC; Wilson JS; Apte MV, 2021, 'Circulating tumour cells in pancreatic cancer: A systematic review and meta-analysis of clinicopathological implications', Pancreatology, 21, pp. 103 - 114, http://dx.doi.org/10.1016/j.pan.2020.11.022
Journal articles | 2021
Pang TCY; Xu Z; Mekapogu AR; Pothula S; Becker T; Corley S; Wilkins MR; Goldstein D; Pirola R; Wilson J; Apte M, 2021, 'Hgf/c-met inhibition as adjuvant therapy improves outcomes in an orthotopic mouse model of pancreatic cancer', Cancers, 13, pp. 2763, http://dx.doi.org/10.3390/cancers13112763
Journal articles | 2021
Powter B; Jeffreys SA; Sareen H; Cooper A; Brungs D; Po J; Roberts T; Koh ES; Scott KF; Sajinovic M; Vessey JY; de Souza P; Becker TM, 2021, 'Human TERT promoter mutations as a prognostic biomarker in glioma', Journal of Cancer Research and Clinical Oncology, 147, pp. 1007 - 1017, http://dx.doi.org/10.1007/s00432-021-03536-3
Journal articles | 2021
Sun J; Stewart P; Chiew A; Becker T; Siu W; Varndell W; Chan BS, 2021, 'Association between shift work and cognitive performance on the Trail Making Test in emergency department health officers', EMA - Emergency Medicine Australasia, 33, pp. 711 - 717, http://dx.doi.org/10.1111/1742-6723.13753
Journal articles | 2021
Tincknell G; Piper AK; Aghmesheh M; Becker T; Vine KL; Brungs D; Ranson M, 2021, 'Experimental and clinical evidence supports the use of urokinase plasminogen activation system components as clinically relevant biomarkers in gastroesophageal adenocarcinoma', Cancers, 13, http://dx.doi.org/10.3390/cancers13164097
Journal articles | 2021
Wilkinson K; Ng W; Roberts TL; Becker TM; Lim SHS; Chua W; Lee CS, 2021, 'Tumour immune microenvironment biomarkers predicting cytotoxic chemotherapy efficacy in colorectal cancer', Journal of Clinical Pathology, 74, pp. 625 - 634, http://dx.doi.org/10.1136/jclinpath-2020-207309
Journal articles | 2020
Brungs D; Minaei E; Piper AK; Perry J; Splitt A; Carolan M; Ryan S; Wu XJ; Corde S; Tehei M; Aghmesheh M; Vine KL; Becker TM; Ranson M, 2020, 'Establishment of novel long-term cultures from EpCAM positive and negative circulating tumour cells from patients with metastatic gastroesophageal cancer', Scientific Reports, 10, http://dx.doi.org/10.1038/s41598-019-57164-6
Journal articles | 2020
Jeffreys SA; Powter B; Balakrishnar B; Mok K; Soon P; Franken A; Neubauer H; Souza PD; Becker TM, 2020, 'Endocrine resistance in breast cancer: The role of estrogen receptor stability', Cells, 9, pp. 1 - 23, http://dx.doi.org/10.3390/cells9092077
Journal articles | 2020
Khan T; Scott KF; Becker TM; Lock J; Nimir M; Ma Y; De Souza P, 2020, 'The Prospect of Identifying Resistance Mechanisms for Castrate-Resistant Prostate Cancer Using Circulating Tumor Cells: Is Epithelial-to-Mesenchymal Transition a Key Player?', Prostate Cancer, 2020, http://dx.doi.org/10.1155/2020/7938280
Journal articles | 2020
Lynch D; Powter B; Po JW; Cooper A; Garrett C; Koh ES; Sheridan M; van Gelder J; Darwish B; Mckechnie S; Bazina R; Jaeger M; Roberts TL; de Souza P; Becker TM, 2020, 'Isolation of circulating tumor cells from glioblastoma patients by direct immunomagnetic targeting', Applied Sciences (Switzerland), 10, http://dx.doi.org/10.3390/app10093338
Journal articles | 2020
Pang TCY; Xu Z; Mekapogu AR; Pothula S; Becker TM; Goldstein D; Pirola RC; Wilson JS; Apte MV, 2020, 'An Orthotopic Resectional Mouse Model of Pancreatic Cancer', Journal of Visualized Experiments, http://dx.doi.org/10.3791/61726-v
Journal articles | 2020
Pang TCY; Xu Z; Mekapogu AR; Pothula S; Becker TM; Goldstein D; Pirola RC; Wilson JS; Apte MV, 2020, 'An orthotopic resectional mouse model of pancreatic cancer', Journal of Visualized Experiments, 2020, pp. 1 - 13, http://dx.doi.org/10.3791/61726
Journal articles | 2020
Sareen H; Garrett C; Lynch D; Powter B; Brungs D; Cooper A; Po J; Koh ES; Vessey JY; McKechnie S; Bazina R; Sheridan M; van Gelder J; Darwish B; Jaeger M; Roberts TL; De Souza P; Becker TM, 2020, 'The role of liquid biopsies in detecting molecular tumor biomarkers in brain cancer patients', Cancers, 12, pp. 1 - 16, http://dx.doi.org/10.3390/cancers12071831
Journal articles | 2019
Brungs D; Lochhead A; Iyer A; Illemann M; Colligan P; Hirst NG; Splitt A; Liauw W; Vine KL; Pathmanandavel S; Carolan M; Becker TM; Aghmesheh M; Ranson M, 2019, 'Expression of cancer stem cell markers is prognostic in metastatic gastroesophageal adenocarcinoma', Pathology, 51, pp. 474 - 480, http://dx.doi.org/10.1016/j.pathol.2019.03.009
Journal articles | 2019
Ding PN; Becker T; Bray V; Chua W; Ma Y; Xu B; Lynch D; de Souza P; Roberts T, 2019, 'Plasma next generation sequencing and droplet digital PCR-based detection of epidermal growth factor receptor (EGFR) mutations in patients with advanced lung cancer treated with subsequent-line osimertinib', Thoracic Cancer, 10, pp. 1879 - 1884, http://dx.doi.org/10.1111/1759-7714.13154
Journal articles | 2019
Ding PN; Becker TM; Bray VJ; Chua W; Ma YF; Lynch D; Po J; Luk AWS; Caixeiro N; de Souza P; Roberts TL, 2019, 'The predictive and prognostic significance of liquid biopsy in advanced epidermal growth factor receptor-mutated non-small cell lung cancer: A prospective study', Lung Cancer, 134, pp. 187 - 193, http://dx.doi.org/10.1016/j.lungcan.2019.06.021
Journal articles | 2019
Nimir M; Ma Y; Jeffreys SA; Opperman T; Young F; Khan T; Ding P; Chua W; Balakrishnar B; Cooper A; Souza PD; Becker TM, 2019, 'Detection of AR-v7 in liquid biopsies of castrate resistant prostate cancer patients: A comparison of AR-v7 analysis in circulating tumor cells, circulating tumor RNA and exosomes', Cells, 8, http://dx.doi.org/10.3390/cells8070688
Journal articles | 2019
Po JW; Ma Y; Balakrishna B; Brungs D; Azimi F; De Souza P; Becker TM, 2019, 'Immunomagnetic isolation of circulating melanoma cells and detection of PD-L1 status', PLoS ONE, 14, http://dx.doi.org/10.1371/journal.pone.0211866
Journal articles | 2019
Singh P; de Souza P; Scott KF; Hall BM; Verma ND; Becker TM; Toh JWT; Sajinovic M; Spring KJ, 2019, 'Biomarkers in immune checkpoint inhibition therapy for cancer patients: what is the role of lymphocyte subsets and PD1/PD-L1?', Translational Medicine Communications, 4, http://dx.doi.org/10.1186/s41231-019-0032-9
Journal articles | 2018
Brungs D; Lynch D; Luk AWS; Minaei E; Ranson M; Aghmesheh M; Vine KL; Carolan M; Jaber M; De Souza P; Becker TM, 2018, 'Cryopreservation for delayed circulating tumor cell isolation is a valid strategy for prognostic association of circulating tumor cells in gastroesophageal cancer', World Journal of Gastroenterology, 24, pp. 810 - 818, http://dx.doi.org/10.3748/wjg.v24.i7.810
Journal articles | 2018
Ding PN; Ma YF; Roberts TJ; Chua W; Bray VJ; Lynch D; Burke D; Souza PD; Becker TM, 2018, 'Droplet Digital PCR Based Detection of EGFR Mutations in Advanced Lung Cancer Patient Liquid Biopsies: A Comparison of Circulating Tumour DNA Extraction Kits', Journal of Molecular Biomarkers & Diagnosis, 09, http://dx.doi.org/10.4172/2155-9929.1000397
Journal articles | 2018
Pang T; Xu Z; Pothula S; Yang MH; Becker T; Goldstein D; Heeschen C; Pirola R; Wilson J; Apte MV, 2018, '517 - World-First Identification of Circulating Pancreatic Stellate Cells in Metastatic Pancreatic Cancer', Gastroenterology, 154, pp. S - 114, http://dx.doi.org/10.1016/s0016-5085(18)30816-3
Journal articles | 2018
Po JW; Roohullah A; Lynch D; DeFazio A; Harrison M; Harnett PR; Kennedy C; Kennedy C; De Souza P; Becker TM, 2018, 'Improved ovarian cancer EMT-CTC isolation by immunomagnetic targeting of epithelial EpCAM and mesenchymal N-cadherin', Journal of Circulating Biomarkers, 7, http://dx.doi.org/10.33393/jcb.2018.2090
Journal articles | 2018
Po JW; Roohullah A; Lynch D; DeFazio A; Harrison M; Harnett PR; Kennedy C; de Souza P; Becker TM, 2018, 'Improved ovarian cancer EMT-CTC isolation by immunomagnetic targeting of epithelial EpCAM and mesenchymal N-cadherin', Journal of Circulating Biomarkers, 7, http://dx.doi.org/10.1177/1849454418782617
Journal articles | 2017
Brungs D; Chen J; Aghmesheh M; Vine KL; Becker TM; Carolan MG; Ranson M, 2017, 'The urokinase plasminogen activation system in gastroesophageal cancer: A systematic review and meta-analysis', Oncotarget, 8, pp. 23099 - 23109, http://dx.doi.org/10.18632/oncotarget.15485
Journal articles | 2017
Ding PN; Roberts TL; Chua W; Becker TM; Descallar J; Yip PY; Bray V, 2017, 'Clinical outcomes in patients with advanced epidermal growth factor receptor-mutated non-small-cell lung cancer in South Western Sydney Local Health District', Internal Medicine Journal, 47, pp. 1405 - 1411, http://dx.doi.org/10.1111/imj.13555
Journal articles | 2017
Luk AWS; Ma Y; Ding PN; Young FP; Chua W; Balakrishnar B; Dransfield DT; De Souza P; Becker TM, 2017, 'CTC-mRNA (AR-V7) analysis from blood samples—impact of blood collection tube and storage time', International Journal of Molecular Sciences, 18, http://dx.doi.org/10.3390/ijms18051047
Journal articles | 2017
Pang TCY; Xu Z; Pothula S; Becker T; Goldstein D; Pirola RC; Wilson JS; Apte MV, 2017, 'Circulating pancreatic stellate (stromal) cells in pancreatic cancer-a fertile area for novel research', Carcinogenesis, 38, pp. 588 - 591, http://dx.doi.org/10.1093/carcin/bgx030
Journal articles | 2016
Brungs D; Aghmesheh M; Vine KL; Becker TM; Carolan MG; Ranson M, 2016, 'Gastric cancer stem cells: evidence, potential markers, and clinical implications', Journal of Gastroenterology, http://dx.doi.org/10.1007/s00535-015-1125-5
Journal articles | 2016
Ma Y; Luk A; Young FP; Lynch D; Chua W; Balakrishnar B; de Souza P; Becker TM, 2016, 'Droplet digital PCR based androgen receptor variant 7 (AR-V7) detection from prostate cancer patient blood biopsies', International Journal of Molecular Sciences, 17, http://dx.doi.org/10.3390/ijms17081264
Journal articles | 2015
Tognela A; Spring KJ; Becker T; Caixeiro NJ; Bray VJ; Yip PY; Chua W; Lim SH; de Souza P, 2015, 'Predictive and prognostic value of circulating tumor cell detection in lung cancer: A clinician's perspective', Critical Reviews in Oncology/Hematology, 93, pp. 90 - 102, http://dx.doi.org/10.1016/j.critrevonc.2014.10.001
Journal articles | 2014
Becker TM; Boyd SC; Mijatov B; Gowrishankar K; Snoyman S; Pupo GM; Scolyer RA; Mann GJ; Kefford RF; Zhang XD; Rizos H, 2014, 'Mutant B-RAF-Mcl-1 survival signaling depends on the STAT3 transcription factor', ONCOGENE, 33, pp. 1158 - 1166, http://dx.doi.org/10.1038/onc.2013.45
Journal articles | 2014
Becker TM; Caixeiro NJ; Lim SH; Tognela A; Kienzle N; Scott KF; Spring KJ; De Souza P, 2014, 'New frontiers in circulating tumor cell analysis: A reference guide for biomolecular profiling toward translational clinical use', International Journal of Cancer, 134, pp. 2523 - 2533, http://dx.doi.org/10.1002/ijc.28516
Journal articles | 2014
Caixeiro NJ; Kienzle N; Lim SH; Spring KJ; Tognela A; Scott KF; De Souza P; Becker TM, 2014, 'Circulating tumour cells - A bona fide cause of metastatic cancer', Cancer and Metastasis Reviews, 33, pp. 747 - 756, http://dx.doi.org/10.1007/s10555-014-9502-8
Journal articles | 2014
Caixeiro NJ; Kienzle N; Lim SH; Spring KJ; Tognela A; Scott KF; de Souza P; Becker TM, 2014, 'Circulating tumour cells-a bona fide cause of metastatic cancer', Cancer and Metastasis Reviews, http://dx.doi.org/10.1007/s10555-014-9502-8
Journal articles | 2014
Lim SH; Becker TM; Chua W; Caixeiro NJ; Ng WL; Kienzle N; Tognela A; Lumba S; Rasko JEJ; De Souza P; Spring KJ, 2014, 'Circulating tumour cells and circulating free nucleic acid as prognostic and predictive biomarkers in colorectal cancer', Cancer Letters, 346, pp. 24 - 33, http://dx.doi.org/10.1016/j.canlet.2013.12.019
Journal articles | 2014
Lim SHS; Becker TM; Chua W; Ng WL; De Souza P; Spring KJ, 2014, 'Circulating tumour cells and the epithelial mesenchymal transition in colorectal cancer', Journal of Clinical Pathology, 67, pp. 848 - 853, http://dx.doi.org/10.1136/jclinpath-2014-202499
Todd JR; Scurr LL; Becker TM; Kefford RF; Rizos H, 2014, 'The MAPK pathway functions as a redundant survival signal that reinforces the PI3K cascade in c-Kit mutant melanoma', ONCOGENE, 33, pp. 236 - 245, http://dx.doi.org/10.1038/onc.2012.562
Journal articles | 2013
Boyd SC; Mijatov B; Pupo GM; Tran SL; Gowrishankar K; Shaw HM; Goding CR; Scolyer RA; Mann GJ; Kefford RF; Rizos H; Becker TM, 2013, 'Oncogenic B-RAFV(600E) Signaling Induces the T-Box3 Transcriptional Repressor to Repress E-Cadherin and Enhance Melanoma Cell Invasion', JOURNAL OF INVESTIGATIVE DERMATOLOGY, 133, pp. 1269 - 1277, http://dx.doi.org/10.1038/jid.2012.421
Journal articles | 2013
Carlino MS; Gowrishankar K; Saunders CAB; Pupo GM; Snoyman S; Zhang XD; Saw R; Becker TM; Kefford RF; Long GV; Rizos H, 2013, 'Antiproliferative Effects of Continued Mitogen-Activated Protein Kinase Pathway Inhibition following Acquired Resistance to BRAF and/or MEK Inhibition in Melanoma', MOLECULAR CANCER THERAPEUTICS, 12, pp. 1332 - 1342, http://dx.doi.org/10.1158/1535-7163.MCT-13-0011
Journal articles | 2013
Gowrishankar K; Snoyman S; Pupo GM; Becker TM; Kefford RF; Rizos H, 2013, 'Acquired Resistance to BRAF Inhibition Can Confer Cross-Resistance to Combined BRAF/MEK Inhibition', Journal of Investigative Dermatology, 133, pp. 2493 - 2493, http://dx.doi.org/10.1038/jid.2013.125
Journal articles | 2013
Haferkamp S; Borst A; Adam C; Becker TM; Motschenbacher S; Windhoevel S; Hufnagel AL; Houben R; Meierjohann S, 2013, 'Vemurafenib Induces Senescence Features in Melanoma Cells', JOURNAL OF INVESTIGATIVE DERMATOLOGY, 133, pp. 1601 - 1609, http://dx.doi.org/10.1038/jid.2013.6
Gowrishankar K; Snoyman S; Pupo GM; Becker TM; Kefford RF; Rizos H, 2012, 'Acquired Resistance to BRAF Inhibition Can Confer Cross-Resistance to Combined BRAF/MEK Inhibition', JOURNAL OF INVESTIGATIVE DERMATOLOGY, 132, pp. 1850 - 1859, http://dx.doi.org/10.1038/jid.2012.63
Journal articles | 2012
Tran SL; Haferkamp S; Scurr LL; Gowrishankar K; Becker TM; Desilva C; Thompson JF; Scolyer RA; Kefford RF; Rizos H, 2012, 'Absence of distinguishing senescence traits in human melanocytic nevi', Journal of Investigative Dermatology, 132, pp. 2226 - 2234, http://dx.doi.org/10.1038/jid.2012.126
Journal articles | 2011
Scurr LL; McKenzie HA; Becker TM; Irvine M; Lai K; Mann GJ; Scolyer RA; Kefford RF; Rizos H, 2011, 'Selective loss of wild-type p16 INK4a expression in human nevi', Journal of Investigative Dermatology, 131, pp. 2329 - 2332, http://dx.doi.org/10.1038/jid.2011.197
Journal articles | 2010
Becker TM; Philipsz S; Scurr LL; Fung C; Haferkamp S; Kefford RF; Rizos H, 2010, 'Oncogenic B-RAF(V600E) Promotes Anchorage-Independent Survival of Human Melanocytes', JOURNAL OF INVESTIGATIVE DERMATOLOGY, 130, pp. 2144 - 2147, http://dx.doi.org/10.1038/jid.2010.117
Journal articles | 2010
Irvine M; Philipsz S; Frausto M; Mijatov B; Gallagher SJ; Fung C; Becker TM; Kefford RF; Rizos H, 2010, 'Amino terminal hydrophobic import signals target the p14(ARF) tumor suppressor to the mitochondria', CELL CYCLE, 9, pp. 829 - 839, http://dx.doi.org/10.4161/cc.9.4.10785
Journal articles | 2010
Jiang CC; Lai F; Tay KH; Croft A; Rizos H; Becker TM; Yang F; Liu H; Thorne RF; Hersey P; Zhang XD, 2010, 'Apoptosis of human melanoma cells induced by inhibition of B-RAF V600E involves preferential splicing of bimS', Cell Death and Disease, 1, http://dx.doi.org/10.1038/cddis.2010.48
Journal articles | 2010
McKenzie HA; Fung C; Becker TM; Irvine M; Mann GJ; Kefford RF; Rizos H, 2010, 'Predicting Functional Significance of Cancer-Associated p16(INK4a) Mutations in CDKN2A', HUMAN MUTATION, 31, pp. 692 - 701, http://dx.doi.org/10.1002/humu.21245
Journal articles | 2010
Scurr LL; Pupo GM; Becker TM; Lai K; Schrama D; Haferkamp S; Irvine M; Scolyer RA; Mann GJ; Becker JC; Kefford RF; Rizos H, 2010, 'IGFBP7 Is Not Required for B-RAF-Induced Melanocyte Senescence', Cell, 141, pp. 717 - 727, http://dx.doi.org/10.1016/j.cell.2010.04.021
Journal articles | 2010
Zhang XD; Jiang CC; Lai F; Croft A; Tay KH; Thorne RF; Becker T; Rizos H; Hersey P, 2010, 'Abstract 1790: Apoptotic response of mutant B-RAF human melanoma cells to a B-RAF inhibitor involves increased splicing production of BimS', Cancer Research, 70, pp. 1790 - 1790, http://dx.doi.org/10.1158/1538-7445.am10-1790
Journal articles | 2009
Becker TM; Haferkamp S; Dijkstra MK; Scurr LL; Frausto M; Diefenbach E; Scolyer RA; Reisman DN; Mann GJ; Kefford RF; Rizos H, 2009, 'The chromatin remodelling factor BRG1 is a novel binding partner of the tumor suppressor p16(INK4a)', MOLECULAR CANCER, 8, http://dx.doi.org/10.1186/1476-4598-8-4
Journal articles | 2009
Haferkamp S; Scurr LL; Becker TM; Frausto M; Kefford RF; Rizos H, 2009, 'Oncogene-Induced Senescence Does Not Require the p16(INK4a) or p14ARF Melanoma Tumor Suppressors', JOURNAL OF INVESTIGATIVE DERMATOLOGY, 129, pp. 1983 - 1991, http://dx.doi.org/10.1038/jid.2009.5
Journal articles | 2009
Haferkamp S; Tran SL; Becker TM; Scurr LL; Kefford RF; Rizos H, 2009, 'The relative contributions of the p53 and pRb pathways in oncogene induced melanocyte senescence', AGING-US, 1, pp. 542 - 556, http://dx.doi.org/10.18632/aging.100051
Journal articles | 2009
McKenzie H; Becker TM; Scurr LL; Kefford RF; Rizos H, 2009, 'Wild type and melanoma-associated mutant p16(INK4a) proteins do not oligomerize in vivo', PIGMENT CELL & MELANOMA RESEARCH, 22, pp. 131 - 133, http://dx.doi.org/10.1111/j.1755-148X.2008.00530.x
Journal articles | 2008
Haferkamp S; Becker TM; Scurr LL; Kefford RF; Rizos H, 2008, 'p16(INK4a)-induced senescence is disabled by melanoma-associated mutations', AGING CELL, 7, pp. 733 - 745, http://dx.doi.org/10.1111/j.1474-9726.2008.00422.x
Journal articles | 2006
Rizos H; McKenzie HA; Ayub AL; Woodruff S; Becker TM; Scurr LL; Stahl J; Kefford RF, 2006, 'Physical and functional interaction of the p14(ARF) tumor suppressor with ribosomes', JOURNAL OF BIOLOGICAL CHEMISTRY, 281, pp. 38080 - 38088, http://dx.doi.org/10.1074/jbc.M609405200
Journal articles | 2005
Becker TM; Ayub AL; Kefford RF; Mann GJ; Rizos H, 2005, 'The melanoma-associated 24 base pair duplication in p16INK4a is functionally impaired', INTERNATIONAL JOURNAL OF CANCER, 117, pp. 569 - 573, http://dx.doi.org/10.1002/ijc.21265
Journal articles | 2005
Becker TM; Rizos H; de la Pena A; Leclercq IA; Woodruff S; Kefford RF; Mann GJ, 2005, 'Impaired inhibition of NF-kappa B activity by melanoma-associated p16INK4a mutations', BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 332, pp. 873 - 879, http://dx.doi.org/10.1016/j.bbrc.2005.05.032
Journal articles | 2003
Fung DCY; Holland EA; Becker TM; Hayward NK; Bressac-de Paillerets B; Mann GJ, 2003, 'eMelanoBase: an online locus-specific variant database for familial melanoma', Human Mutation, 21, pp. 2 - 7, http://dx.doi.org/10.1002/humu.10149
Journal articles | 2003
Rizos H; Diefenbach E; Badhwar P; Woodruff S; Becker TM; Rooney RJ; Kefford RF, 2003, 'Association of p14(ARF) with the p120(E4F) transcriptional repressor enhances cell cycle inhibition', JOURNAL OF BIOLOGICAL CHEMISTRY, 278, pp. 4981 - 4989, http://dx.doi.org/10.1074/jbc.M210978200
Holland EA; Becker TM; Kefford RF; Mann GJ, 1997, 'Mutation analysis of CDKN2A and CDK4 in familial melanoma', Melanoma Research, 7, pp. S133 - S133, http://dx.doi.org/10.1097/00008390-199706001-00463
Journal articles | 1997
Rizos H; Becker TM; Holland EA; Kefford RF; Mann GJ, 1997, 'Differential expression of p16(INK4a) and p16 beta transcripts in B-lymphoblastoid cells from members of hereditary melanoma families without CDKN2A exon mutations', ONCOGENE, 15, pp. 515 - 523, http://dx.doi.org/10.1038/sj.onc.1201217
Journal articles | 1995
Holland EA; Beaten SC; Becker TM; Grulet OMC; Peters BA; Rizos H; Kefford RF; Mann GJ, 1995, 'Analysis of the p16 gene, CDKN2, in 17 Australian melanoma kindreds', Oncogene, 11, pp. 2289 - 2294
Preprints | 2024
Chan WY; Chua W; Wilkinson K; Epitakaduwa C; Mandaliya H; Descallar J; Roberts TL; Becker TM; Ng W; Lee CS; Lim SH, 2024, The Prognostic and Predictive Utility of CDX2 in Colorectal Cancer, http://dx.doi.org/10.20944/preprints202407.1687.v1
Conference Abstracts | 2024
Lea V; Lim SH-S; Chua W; Ng WL; Wang B; Wilkinson KJ; Farzin M; Habashy P; Roberts T; Becker T; Lee CS, 2024, 'Incidence and potential prognostic implications of fibroblast growth factor receptor gene alterations and coexisting mutations in colorectal cancer', in JOURNAL OF CLINICAL ONCOLOGY, LIPPINCOTT WILLIAMS & WILKINS, ELECTR NETWORK, Vol. 42, presented at Special Clinical Science Symposia, ELECTR NETWORK, 29 May 2024 - 29 May 2024
Preprints | 2023
El-Kamand S; Quinn JMW; Sareen H; Becker T; Wong-Erasmus M; Cowley M, 2023, CRUX, a platform for visualising, exploring and analysing cancer genome cohort data, http://dx.doi.org/10.1101/2023.07.25.550585
Conference Abstracts | 2023
Marivel A-MJ; Roberts TL; Descallar J; Aung WPP; Cheng J; Becker TM; James A; Ma Y; Bryant A; Ling S, 2023, 'Multiple Myeloma in the Culturally and Linguistically Diverse Southwestern Sydney, Australia', in BLOOD, ELSEVIER, CA, San Diego, Vol. 142, presented at 65th Annual Meeting of the American-Society-of-Hematology (ASH), CA, San Diego, 09 December 2023 - 12 December 2023, http://dx.doi.org/10.1182/blood-2023-185193
Preprints | 2022
Khan T; Lock J; Ma Y; Harman D; Souza P; Chua W; Balakrishnar B; Scott KF; Becker TM, 2022, Choice of antibody is critical for specific and sensitive detection of androgen receptor splice variant-7 in circulating tumor cells, http://dx.doi.org/10.21203/rs.3.rs-1602818/v1
Preprints | 2022
Khan T; Lock J; Ma Y; Harman D; Souza P; Chua W; Balakrishnar B; Scott KF; Becker TM, 2022, Choice of antibody is critical for specific and sensitive detection of androgen receptor splice variant-7 in circulating tumor cells, http://dx.doi.org/10.21203/rs.3.rs-1602818/v2
Conference Abstracts | 2022
Nindra U; Pal A; Jasti S; Lim SH-S; Bray V; Yip PY; Tognela A; Ashgari R; Roberts T; Becker T; Liauw W; Farzin M; Ng W; Lee S; Chua W, 2022, 'The utility of multigene panel next generation sequencing in routine clinical practice for identifying genomic alterations in CRC and NSCLC', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY, Vol. 18, pp. 45 - 46
Conference Papers | 2021
Leathem S; Chiew A; Becker T; Chan B, 2021, 'Case report of caustic ingestion with delayed presentation', in TOXICOLOGY COMMUNICATIONS, TAYLOR & FRANCIS LTD, pp. 122 - 122
Conference Papers | 2021
Tincknell G; Piper A-K; Ma Y; Ranson M; Becker T; Brungs D, 2021, 'Tracking circulating tumour DNA in patients with resectable gastroesophageal cancer', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY, pp. 43 - 43
Pang T; Mekapogu AR; Xu Z; Pothula S; Goldstein D; Pirola R; Wilson J; Becker T; Apte M, 2020, 'Characterization of circulating pancreatic stellate cells in pancreatic cancer by single-cell transcriptomic analysis', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY, pp. 161 - 162
Ding PN; Becker T; Bray VJ; Chua W; Ma YF; Luk A; Po J; Lynch D; Caixeiro N; de Souza P; Roberts TL, 2018, 'Longitudinal analysis of circulating biomarkers to monitor advanced EGFR mutated (EGFR+) non-small cell lung cancer (NSCLC)', in Annals of oncology : official journal of the European Society for Medical Oncology, pp. viii660, http://dx.doi.org/10.1093/annonc/mdy303.033
Wilson J; Pang T; Xu Z; Mekapogu A; Pothula S; Goldstein D; Pirola R; Wilson J; Apte M, 2018, 'Establishment of a noval adjuvant model of orthotopic pancreatic cancer: effects of HGF-cMET inhibition on disease progression', Sydney, presented at Avner Cancer Symposium, Sydney
Chen JYJ; Brungs D; Aghmesheh M; Perrow K; Becker T; Carolan M; Ranson M, 2016, 'EXPRESSION OF UROKINASE PLASMINOGEN ACTIVATION SYSTEM IN PRIMARY GASTRO-ESOPHAGEAL ADENOCARCINOMA: A SYSTEMATIC REVIEW AND META-ANALYSIS', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY-BLACKWELL, pp. 105 - 105
Conference Abstracts | 2015
Lim SH; Spring K; Chua W; Ng W; Descallar J; Ma Y; Becker TM; De Souza P, 2015, 'Circulating Tumor Cells in Locally Advanced Rectal Cancer Treated With Neoadjuvant Chemoradiation', in INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, ELSEVIER SCIENCE INC, TX, San Antonio, Vol. 93, pp. E522 - E523, presented at 57th Annual Meeting of the American-Society-for-Radiation-Oncology (ASTRO), TX, San Antonio, 18 October 2015 - 21 October 2015, http://dx.doi.org/10.1016/j.ijrobp.2015.07.1883