Dr Sarah Sasson

Dr Sarah Sasson

Senior Lecturer

BA(English) BSc (Hons I Immunology) MBBS(Hons) PhD FRACP FRCPA

Medicine & Health
The Kirby Institute

Sarah is a Clinical Immunologist/Immunopathologist and Scientia Senior Lecturer. She graduated from a BSc(HonsI)/BA (English) prior to a combined MBBS(Hons)/PhD program. Sarah completed specialist medical training in Clinical Immunology and Immunopathology at St Vincent's, Royal Prince Alfred, Concord, Liverpool and Campbelltown Hospitals and gained dual fellowships of the Royal Australasian College of Physicians and Royal College of Pathologists Australasia in 2017. From 2018-2019 Sarah undertook postdoctoral studies at the University of Oxford investigating autoimmune toxicities of immune checkpoint inhibitors in Professor Paul Klenerman's laboratory.

Sarah's broad research area is human translational Immunology. Her particular interests include the role of  T cells in the control of cancers and sepsis as well as COVID-19 in immunocompromised people.

Broad Research Areas:
Immunology, Infectious Diseases, Cancer Immunology, Immune Checkpoint Inhibitors, Mucosal Immunology, Sepsis

Qualifications:
BA, BSc(Hons I), MBBS(Hons), PhD, FRACP, FRCPA

Publications:

https://www.ncbi.nlm.nih.gov/myncbi/1limy-hBarikX/bibliography/public/

Phone
83822829
  • Journal articles | 2024
    Gupta T; Antanaviciute A; Hyun-Jung Lee C; Ottakandathil Babu R; Aulicino A; Christoforidou Z; Siejka-Zielinska P; O'Brien-Ball C; Chen H; Fawkner-Corbett D; Geros AS; Bridges E; McGregor C; Cianci N; Fryer E; Alham NK; Jagielowicz M; Santos AM; Fellermeyer M; Davis SJ; Parikh K; Cheung V; Al-Hillawi L; Sasson S; Slevin S; Brain O; Bird-Lieberman E; Fourie S; Johnston R; Joshi H; Mujamdar D; Panter S; Patodi N; Shaji S; Tidbury J; Verma A; Fernandes RA; Koohy H; Simmons A, 2024, 'Tracking in situ checkpoint inhibitor-bound target T cells in patients with checkpoint-induced colitis', Cancer Cell, 42, pp. 797 - 814.e15, http://dx.doi.org/10.1016/j.ccell.2024.04.010
    Journal articles | 2024
    Hastak P; Cromer D; Malycha J; Andersen CR; Raith E; Davenport MP; Plummer M; Sasson SC, 2024, 'Defining the correlates of lymphopenia and independent predictors of poor clinical outcome in adults hospitalized with COVID-19 in Australia', Scientific Reports, 14, http://dx.doi.org/10.1038/s41598-024-61729-5
    Journal articles | 2024
    Revoltar M; van der Linde R; Cromer D; Gatt PN; Smith S; Fernandez MA; Vaughan L; Blyth E; Curnow J; Tegg E; Brown DA; Sasson SC, 2024, 'Indeterminate measurable residual disease by multiparameter flow cytometry is associated with an intermediate risk of clinical relapse in adult patients with acute leukaemia', Pathology, 56, pp. 882 - 888, http://dx.doi.org/10.1016/j.pathol.2024.04.009
    Journal articles | 2024
    Wu L; Carlino MS; Brown DA; Long GV; Clifton-Bligh R; Mellor R; Moore K; Sasson SC; Menzies AM; Tsang V; Gunton JE, 2024, 'Checkpoint Inhibitor-Associated Autoimmune Diabetes Mellitus Is Characterized by C-peptide Loss and Pancreatic Atrophy', Journal of Clinical Endocrinology and Metabolism, 109, pp. 1301 - 1307, http://dx.doi.org/10.1210/clinem/dgad685
    Journal articles | 2024
    Wu L; Carlino MS; Brown DA; Long GV; Clifton-Bligh R; Mellor R; Moore K; Sasson SC; Menzies AM; Tsang V; Gunton JE, 2024, 'Response to Letter to the Editor from Hao and Xue: "Checkpoint Inhibitor-Associated Autoimmune Diabetes Mellitus Is Characterized by C-peptide Loss and Pancreatic Atrophy".', J Clin Endocrinol Metab, http://dx.doi.org/10.1210/clinem/dgae555
    Journal articles | 2024
    Wu L; Wentworth J; Liddle C; Carlino M; Brown D; Clifton-Bligh RJ; Long G; Sasson S; Tsang V; Menzies A; Gunton JE, 2024, '7760 Identifying Conventional and Novel Biomarkers to Predict Checkpoint Inhibitor Associated Autoimmune Diabetes', Journal of the Endocrine Society, 8, http://dx.doi.org/10.1210/jendso/bvae163.803
    Journal articles | 2024
    van der Linde R; Gatt PN; Smith S; Fernandez M; Vaughan L; Blyth E; Curnow J; Brown DA; Tegg E; Sasson SC, 2024, 'Correlation of flow cytometric measurable residual disease (FC-MRD) with molecular MRD and clinical outcome at one year in adult B-acute lymphoblastic leukaemia (B-ALL) and acute myeloid leukaemia (AML)', Pathology, 56, pp. S108 - S108, http://dx.doi.org/10.1016/j.pathol.2023.12.359
    Journal articles | 2023
    Barreto SG; Kaambwa B; Venkatesh K; Sasson SC; Andersen C; Delaney A; Bihari S; Pilcher D, 2023, 'Mortality and costs related to severe acute pancreatitis in the intensive care units of Australia and New Zealand (ANZ), 2003–2020', Pancreatology, 23, pp. 341 - 349, http://dx.doi.org/10.1016/j.pan.2023.04.006
    Journal articles | 2023
    Beaton B; Sasson SC; Rankin K; Raedemaeker J; Wong A; Hastak P; Phetsouphanh C; Warden A; Klemm V; Munier CML; Hoppe AC; Tea F; Pillay A; Stella AO; Aggarwal A; Lavee O; Caterson ID; Turville S; Kelleher AD; Brilot F; Trotman J; Carey Hoppe A, 2023, 'Patients with treated indolent lymphomas immunized with BNT162b2 have reduced anti-spike neutralizing IgG to SARS-CoV-2 variants, but preserved antigen-specific T cell responses', American Journal of Hematology, 98, pp. 131 - 139, http://dx.doi.org/10.1002/ajh.26619
    Journal articles | 2023
    Cromer D; Steain M; Reynaldi A; Schlub TE; Khan SR; Sasson SC; Kent SJ; Khoury DS; Davenport MP, 2023, 'Predicting vaccine effectiveness against severe COVID-19 over time and against variants: a meta-analysis', Nature Communications, 14, pp. 1633, http://dx.doi.org/10.1038/s41467-023-37176-7
    Journal articles | 2023
    Dharan NJ; Sasson SC; Ahlenstiel G; Andersen CR; Bloch M; Buckland G; Hamad N; Han WM; Kelleher AD; Long GV; Matthews GV; Mina MM; Papot E; Petoumenos K; Swaminathan S; Withers B; Yun J; Polizzotto MN, 2023, 'Clinical and laboratory features of COVID-19 illness and outcomes in immunocompromised individuals during the first pandemic wave in Sydney, Australia', PLoS ONE, 18, http://dx.doi.org/10.1371/journal.pone.0289907
    Journal articles | 2023
    Finfer S; Venkatesh B; Hotchkiss RS; Sasson SC, 2023, 'Lymphopenia in sepsis—an acquired immunodeficiency?', Immunology and Cell Biology, 101, pp. 535 - 544, http://dx.doi.org/10.1111/imcb.12611
    Journal articles | 2023
    Gupta M; Balachandran H; Louie RHY; Li H; Agapiou D; Keoshkerian E; Christ D; Rawlinson W; Mina MM; Post JJ; Hudson B; Gilroy N; Konecny P; Bartlett AW; Sasson SC; Ahlenstiel G; Dwyer D; Lloyd AR; Martinello M; Luciani F; Bull RA, 2023, 'High activation levels maintained in receptor-binding domain–specific memory B cells in people with severe coronavirus disease 2019', Immunology and Cell Biology, 101, pp. 142 - 155, http://dx.doi.org/10.1111/imcb.12607
    Journal articles | 2023
    Hewavisenti RV; Arena J; Ahlenstiel CL; Sasson SC, 2023, 'Human papillomavirus in the setting of immunodeficiency: Pathogenesis and the emergence of next-generation therapies to reduce the high associated cancer risk', Frontiers in Immunology, 14, http://dx.doi.org/10.3389/fimmu.2023.1112513
    Journal articles | 2023
    Rankin K; Hastak P; Wong A; Sasson SC; Beaton B; Yeola A; Warden A; Turville S; Kelleher AD; Brilot F; Trotman J, 2023, 'Immune response to COVID‐19 vaccination in patients with Waldenström macroglobulinaemia who pause their BTKi therapy', eJHaem, 4, pp. 728 - 732, http://dx.doi.org/10.1002/jha2.724
    Journal articles | 2023
    Reardon B; Smith S; Van Der Linde R; Sasson SC, 2023, 'Use of anti-JOVI.1 antibodies to detect clonal T cell populations: implementation into a diagnostic flow cytometry laboratory and correlation with clinical findings', Pathology, 55, pp. S23 - S23, http://dx.doi.org/10.1016/j.pathol.2022.12.077
    Journal articles | 2023
    Venkatesh K; Glenn H; Delaney A; Andersen CR; Sasson SC, 2023, 'Fire in the belly: A scoping review of the immunopathological mechanisms of acute pancreatitis', Frontiers in Immunology, 13, http://dx.doi.org/10.3389/fimmu.2022.1077414
    Journal articles | 2023
    Wu L; Tsang V; Menzies AM; Sasson SC; Carlino MS; Brown DA; Clifton-Bligh R; Gunton JE, 2023, 'Risk Factors and Characteristics of Checkpoint Inhibitor– Associated Autoimmune Diabetes Mellitus (CIADM): A Systematic Review and Delineation From Type 1 Diabetes', Diabetes Care, 46, pp. 1292 - 1299, http://dx.doi.org/10.2337/dc22-2202
    Journal articles | 2023
    van der Linde R; Gatt PN; Smith S; Fernandez MA; Vaughan L; Blyth E; Curnow J; Brown DA; Tegg E; Sasson SC, 2023, 'Measurable Residual Disease (MRD) by Flow Cytometry in Adult B-Acute Lymphoblastic Leukaemia (B-ALL) and Acute Myeloid Leukaemia (AML): Correlation with Molecular MRD Testing and Clinical Outcome at One Year', Cancers, 15, http://dx.doi.org/10.3390/cancers15205064
    Journal articles | 2023
    van der Linde R; Smith S; Brown DA; Sasson SC; Tegg E, 2023, 'Measurable residual disease in adult acute myeloid leukaemia: evaluation of a multidimensional ‘radar’ flow cytometric plot analysis method', Pathology, 55, pp. 383 - 390, http://dx.doi.org/10.1016/j.pathol.2022.10.007
    Journal articles | 2022
    Adhikari A; Abayasingam A; Rodrigo C; Agapiou D; Pandzic E; Brasher NA; Fernando BSM; Keoshkerian E; Li H; Kim HN; Lord M; Popovic G; Rawlinson W; Mina M; Post JJ; Hudson B; Gilroy N; Dwyer D; Sasson SC; Grubor-Bauk B; Lloyd AR; Martinello M; Bull RA; Tedla N; Kaldor J; Dore G; Sorrell T; Bartlett A; Lemberg D; Di Girolamo N; Byrne M; Hammoud M; Sultan R; Konecny P; Matthews G; Shek D; Holdaway S; Mitsa-Kos K; How-Chow D; Lagunday R; Robinson S; Terrill L; Joshi N; Li Y; Gill S; Sevehon A, 2022, 'Longitudinal Characterization of Phagocytic and Neutralization Functions of Anti-Spike Antibodies in Plasma of Patients after Severe Acute Respiratory Syndrome Coronavirus 2 Infection', Journal of Immunology, 209, pp. 1499 - 1512, http://dx.doi.org/10.4049/jimmunol.2200272
    Journal articles | 2022
    Balachandran H; Phetsouphanh C; Agapiou D; Adhikari A; Rodrigo C; Hammoud M; Shrestha LB; Keoshkerian E; Gupta M; Turville S; Christ D; King C; Sasson SC; Bartlett A; Grubor-Bauk B; Rawlinson W; Aggarwal A; Stella AO; Klemm V; Mina MM; Post JJ; Hudson B; Gilroy N; Konecny P; Ahlenstiel G; Dwyer DE; Sorrell TC; Kelleher A; Tedla N; Lloyd AR; Martinello M; Bull RA, 2022, 'Maintenance of broad neutralizing antibodies and memory B cells 1 year post-infection is predicted by SARS-CoV-2-specific CD4+ T cell responses', Cell Reports, 38, pp. 110345, http://dx.doi.org/10.1016/j.celrep.2022.110345
    Journal articles | 2022
    Hastak PS; Andersen CR; Kelleher AD; Sasson SC, 2022, 'Frontline workers: Mediators of mucosal immunity in community acquired pneumonia and COVID-19', Frontiers in Immunology, 13, http://dx.doi.org/10.3389/fimmu.2022.983550
    Journal articles | 2022
    Kent SJ; Khoury DS; Reynaldi A; Juno JA; Wheatley AK; Stadler E; John Wherry E; Triccas J; Sasson SC; Cromer D; Davenport MP, 2022, 'Disentangling the relative importance of T cell responses in COVID-19: leading actors or supporting cast?', Nature Reviews Immunology, 22, pp. 387 - 397, http://dx.doi.org/10.1038/s41577-022-00716-1
    Journal articles | 2022
    Rankin K; Beaton B; Sasson S; Raedemaecker J; Wong A; Hastak P; Phetsouphanh C; Warden A; Patel M; Klemm V; Munier CML; Carey Hoppe A; Tea F; Pillay A; Ospina A; Aggarwal A; Lavee O; Caterson ID; Turville S; Kelleher AD; Brilot F; Trotman J, 2022, 'PB2087: EFFICACY OF A 3RD COVID VACCINE, INCLUDING DURING A BTKI PAUSE, IN INDIVIDUALS WITH WALDENSTRÖM MACROGLOBULINEMIA AND FOLLICULAR LYMPHOMA', HemaSphere, 6, pp. 1958 - 1959, http://dx.doi.org/10.1097/01.hs9.0000851180.32970.18
    Journal articles | 2021
    Abayasingam A; Balachandran H; Agapiou D; Hammoud M; Rodrigo C; Keoshkerian E; Li H; Brasher NA; Christ D; Rouet R; Burnet D; Grubor-Bauk B; Rawlinson W; Turville S; Aggarwal A; Stella AO; Fichter C; Brilot F; Mina M; Post JJ; Hudson B; Gilroy N; Dwyer D; Sasson SC; Tea F; Pilli D; Kelleher A; Tedla N; Lloyd AR; Martinello M; Bull RA; Burnett D, 2021, 'Long-term persistence of RBD+ memory B cells encoding neutralizing antibodies in SARS-CoV-2 infection', Cell Reports Medicine, 2, pp. 100228, http://dx.doi.org/10.1016/j.xcrm.2021.100228
    Journal articles | 2021
    Beaton B; Sasson SC; Rankin K; Raedemaeker J; Wong A; Hastak P; Warden A; Stella AO; Aggarwal A; Caterson ID; Phetsouphanh C; Turville S; Kelleher AD; Brilot F; Trotman J, 2021, 'Efficacy of Vaccine BNT162b2 (Pfizer-BioNTech) in Individuals with Waldenstrom's Macroglobulinemia and Follicular Lymphoma in Australia', BLOOD, 138, http://dx.doi.org/10.1182/blood-2021-149348
    Journal articles | 2021
    Hargreaves CE; Salatino S; Sasson SC; Charlesworth JEG; Bateman E; Patel AM; Anzilotti C; Broxholme J; Knight JC; Patel SY, 2021, 'Decreased ATM Function Causes Delayed DNA Repair and Apoptosis in Common Variable Immunodeficiency Disorders', Journal of Clinical Immunology, 41, pp. 1315 - 1330, http://dx.doi.org/10.1007/s10875-021-01050-2
    Journal articles | 2021
    Sasson SC; Slevin SM; Cheung VTF; Nassiri I; Olsson-Brown A; Fryer E; Ferreira RC; Trzupek D; Gupta T; Al-Hillawi L; Issaias ML; Easton A; Campo L; FitzPatrick MEB; Adams J; Chitnis M; Protheroe A; Tuthill M; Coupe N; Simmons A; Payne M; Middleton MR; Travis SPL; Fairfax BP; Klenerman P; Brain O, 2021, 'Interferon-Gamma–Producing CD8+ Tissue Resident Memory T Cells Are a Targetable Hallmark of Immune Checkpoint Inhibitor–Colitis', Gastroenterology, 161, pp. 1229 - 1244.e9, http://dx.doi.org/10.1053/j.gastro.2021.06.025
    Journal articles | 2021
    Sasson SC; Wilkins LE; Watson RA; Jolly C; Brain O; Klenerman P; Olsson-Brown A; Fairfax BP, 2021, 'Identification of neutralising pembrolizumab anti-drug antibodies in patients with melanoma', Scientific Reports, 11, http://dx.doi.org/10.1038/s41598-021-98700-7
    Journal articles | 2021
    Sasson SC, 2021, 'Autoimmune toxicities of T cell checkpoint inhibitors', Pathology, 53, pp. S16 - S16, http://dx.doi.org/10.1016/j.pathol.2021.05.058
    Journal articles | 2021
    Wu L; Tsang VHM; Sasson SC; Menzies AM; Carlino MS; Brown DA; Clifton-Bligh R; Gunton JE, 2021, 'Unravelling Checkpoint Inhibitor Associated Autoimmune Diabetes: From Bench to Bedside', Frontiers in Endocrinology, 12, http://dx.doi.org/10.3389/fendo.2021.764138
    Journal articles | 2021
    van der Linde R; Smith S; Sasson SC; Brown D; Tegg E, 2021, 'Use of multidimentional flow cytometry plots to improve measurable residual disease monitoring of acute myeloid leukaemias', Pathology, 53, pp. S46 - S46, http://dx.doi.org/10.1016/j.pathol.2021.06.096
    Journal articles | 2020
    Cheung VT; Gupta T; Olsson-Brown AC; Subramanian S; Sasson SC; Heseltine J; Fryer E; Collantes-Bellido E; Sacco JJ; Pirmohamed M; Simmons A; Klenerman P; Fairfax BP; Payne MJ; Middleton MR; Brain O, 2020, 'Su1185 IMMUNE CHECKPOINT INHIBITOR-RELATED COLITIS ASSESSMENT AND PROGNOSIS: CAN UCEIS, MAYO AND NANCY INDEX SCORING POINT THE WAY?', Gastroenterology, 158, http://dx.doi.org/10.1016/s0016-5085(20)32033-3
    Journal articles | 2020
    Cheung VTF; Gupta T; Olsson-Brown A; Subramanian S; Sasson SC; Heseltine J; Fryer E; Collantes E; Sacco JJ; Pirmohamed M; Simmons A; Klenerman P; Fairfax BP; Payne MJ; Middleton MR; Brain O, 2020, 'P272 Immune checkpoint inhibitor-related colitis assessment and prognosis: can inflammatory bowel disease scoring point the way?', Journal of Crohn's and Colitis, 14, pp. S286 - S288, http://dx.doi.org/10.1093/ecco-jcc/jjz203.401
    Journal articles | 2020
    Cheung VTF; Gupta T; Olsson-Brown A; Subramanian S; Sasson SC; Heseltine J; Fryer E; Collantes E; Sacco JJ; Pirmohamed M; Simmons A; Klenerman P; Tuthill M; Protheroe AS; Chitnis M; Fairfax BP; Payne MJ; Middleton MR; Brain O, 2020, 'Immune checkpoint inhibitor-related colitis assessment and prognosis: can IBD scoring point the way?', British Journal of Cancer, 123, pp. 207 - 215, http://dx.doi.org/10.1038/s41416-020-0882-y
    Journal articles | 2020
    Sasson SC; Gordon CL; Christo SN; Klenerman P; Mackay LK, 2020, 'Local heroes or villains: tissue-resident memory T cells in human health and disease', Cellular and Molecular Immunology, 17, pp. 113 - 122, http://dx.doi.org/10.1038/s41423-019-0359-1
    Journal articles | 2020
    Sasson SC; Zaunders JJ; Nahar K; Munier CML; Fairfax BP; Olsson-Brown A; Jolly C; Read SA; Ahlenstiel G; Palendira U; Scolyer RA; Carlino MS; Payne MJ; Cheung VTF; Gupta T; Klenerman P; Long GV; Brain O; Menzies AM; Kelleher AD, 2020, 'Mucosal-associated invariant T (MAIT) cells are activated in the gastrointestinal tissue of patients with combination ipilimumab and nivolumab therapy-related colitis in a pathology distinct from ulcerative colitis', Clinical and Experimental Immunology, 202, pp. 335 - 352, http://dx.doi.org/10.1111/cei.13502
    Journal articles | 2019
    Sasson SC; Cheung VTF; Gupta T; Zaunders JJ; Nahar K; Munier CM-L; Olsson-Brown A; Ahlenstiel G; Palendira U; Scolyer RA; Carlino MS; Long GV; Menzies AM; Kelleher A; Payne M; Fairfax B; Middleton MR; Klenerman P; Brain O, 2019, '1303P Tissue-based activation of mucosal-associated invariant T (MAIT) cells in combination ipilimumab and nivolumab checkpoint inhibitor (CI) colitis', Annals of Oncology, 30, pp. v530, http://dx.doi.org/10.1093/annonc/mdz253.128
    Journal articles | 2019
    Sasson SC; Corbett A; McLachlan AJ; Chen R; Adelstein SA; Riminton S; Limaye S, 2019, 'Enhanced serum immunoglobulin G clearance in myotonic dystrophy-associated hypogammaglobulinemia: A case series and review of the literature', Journal of Medical Case Reports, 13, pp. 338, http://dx.doi.org/10.1186/s13256-019-2285-3
    Journal articles | 2018
    Deenick EK; Morey A; Danta M; Emmett L; Fay K; Gracie G; Ma CS; Macintosh R; Smith SABC; Sasson SC; Sewell WA; Cowley M; Tangye SG; Kelleher AD; Phan TG, 2018, 'Reversible Suppression of Lymphoproliferation and Thrombocytopenia with Rapamycin in a Patient with Common Variable Immunodeficiency', Journal of Clinical Immunology, 38, pp. 159 - 162, http://dx.doi.org/10.1007/s10875-018-0477-z
    Journal articles | 2017
    Koelsch KK; Rasmussen TA; Hey-Nguyen WJ; Pearson C; Xu Y; Bailey M; Marks KH; Sasson SC; Taylor MS; Tantau R; Obeid S; Milner B; Morrissey O; Pinto AN; Suzuki K; Busch MP; Keating SM; Kaiser P; Yukl S; Wong JK; Hiener BM; Palmer S; Zaunders J; Post JJ; Chan DJ; Avery S; Milliken ST; Kelleher AD; Lewin SR; Cooper DA; Cooper D, 2017, 'Impact of Allogeneic Hematopoietic Stem Cell Transplantation on the HIV Reservoir and Immune Response in 3 HIV-Infected Individuals', Journal of Acquired Immune Deficiency Syndromes, 75, pp. 328 - 337, http://dx.doi.org/10.1097/QAI.0000000000001381
    Journal articles | 2017
    Sasson SC; Russo R; Chung T; Chu G; Hunyor I; Williamson J; Murad A; Kane A; Riminton S; Limaye S, 2017, 'Cardiac magnetic resonance imaging-indeterminate/negative cardiac sarcoidosis revealed by 18F-fluorodeoxyglucose-positron emission tomography: Two case reports and a review of the literature', Journal of Medical Case Reports, 11, http://dx.doi.org/10.1186/s13256-017-1453-6
    Journal articles | 2016
    Anderson S; Sasson SC; Lee FJ; Cooper W; Larsen S; Garsia R, 2016, 'Episodic fevers and vasodilatory shock mimicking urosepsis in a patient with HIV-associated multicentric Castleman's Disease: A case report', BMC Infectious Diseases, 16, pp. 53, http://dx.doi.org/10.1186/s12879-016-1378-5
    Journal articles | 2016
    Sasson SC; Davies S; Chan R; Davies L; Garsia R, 2016, 'Cerebral toxoplasmosis in a patient with myasthenia gravis and thymoma with immunodeficiency/Good's syndrome: A case report', BMC Infectious Diseases, 16, pp. 457, http://dx.doi.org/10.1186/s12879-016-1801-y
    Journal articles | 2015
    Koelsch KK; Hey-Cunningham WJ; Sasson SC; Pearson C; Bailey M; Marks KH; Hiener BM; Palmer S; Zaunders JJ; Post JJ; Milliken ST; Kelleher AD; Cooper DA; Xu Y, 2015, 'Allogeneic bone marrow transplantation in two HIV-1 infected patients shows no detectable HIV-1 RNA or DNA, and a profound reduction in HIV-1 antibodies', Pathology, 47, pp. S55 - S55, http://dx.doi.org/10.1097/01.pat.0000461459.26902.eb
    Journal articles | 2015
    Sasson SC; McGill K; Wienholt L; Carr A; Brown D; Kelleher AD; Breit SN; Sewell WA, 2015, 'Retrospective audit of the freeliteTM serum free light chain (SFLC) assay: testing patterns, concordance with serum and urine electrophoresis/immunofixation and correlation with the N latex FLC assay', Pathology, 47, pp. S94 - S94, http://dx.doi.org/10.1097/01.pat.0000461601.28805.d5
    Journal articles | 2015
    Sasson SC; McGill K; Wienholt L; Carr A; Brown DA; Kelleher AD; Breit SN; Sewell WA, 2015, 'Comparison of the Freelite serum free light chain (SFLC) assay with serum and urine electrophoresis/immunofixation and the N Latex FLC assay', Pathology, 47, pp. 564 - 569, http://dx.doi.org/10.1097/PAT.0000000000000316
    Journal articles | 2015
    Sasson SC; Smith SA; Qiu MR; Stone ECA; Sewell WA, 2015, 'Monoclonal precursor T-cell infiltrate in recurrent thymoma: a case report', Pathology, 47, pp. 375 - 377, http://dx.doi.org/10.1097/PAT.0000000000000257
    Journal articles | 2014
    Sasson S; Smith S; Sewell WA; Morey A; Danta M; Emmett L; Kelleher AD; Fay K; Phan T, 2014, 'MONOCLONAL B-CELL POPULATION OF INDETERMINANT MALIGNANT POTENTIAL IN THE SETTING OF ATYPICAL CVID ASSOCIATED WITH LYMPHADENOPATHY AND SPLENOMEGALY', INTERNAL MEDICINE JOURNAL, 44, pp. 33 - 33, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000342722800109&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 2014
    Sasson SC; Kelleher AD, 2014, 'Site-specific host gene modification by zinc finger nucleases: pointing the way to drug free control of HIV-1?', Clinical and Translational Immunology, 3, pp. e19, http://dx.doi.org/10.1038/cti.2014.12
    Journal articles | 2013
    Sasson SC; Oon A; Chagantri J; Brew BJ; Carr A, 2013, 'Posterior reversible encephalopathy syndrome (PRES) in an HIV-1 infected patient with disseminated varicella zoster virus: a case report', BMC Infectious Diseases, 13, pp. 396 - 396, http://dx.doi.org/10.1186/1471-2334-13-396
    Journal articles | 2012
    Sasson SC; Zaunders J; Seddiki N; Mcbride K; Koelsch KK; Merlin KM; Smith DE; Cooper DA; Kelleher AD; Bailey MR, 2012, 'Progressive activation of CD127+132- recent thymic emigrants into terminally differentiated CD127-132+ T-cells in HIV-1 infection', PLoS One, 7, pp. e31148, http://dx.doi.org/10.1371/journal.pone.0031148
    Journal articles | 2009
    Seddiki N; Sasson SC; Santner-Nanan B; Munier M; Van Bockel DJ; Ip S; Marriott D; Pett SL; Nanan R; Cooper DA; Zaunders J; Kelleher AD, 2009, 'Proliferation of weakly suppressive regulatory CD4+ T cells is associated with over-active CD4+ T-cell responses in HIV-positive patients with mycobacterial immune restoration disease', European Journal of Immunology, 39, pp. 391 - 403, http://dx.doi.org/10.1002/eji.200838630
    Journal articles | 2006
    Fazekos de St Groth B; Seddiki N; Santner-Nanan B; Martinson J; Zaunders J; Sasson SC; Landay A; Nanan R; Kelleher AD, 2006, 'Expression of IL-2 and IL-7 receptors discriminates between human regulatory and activated T-cells within CD45RA and CD45RO compartments', Clinical Immunology, 119, pp. S7 - S7
    Journal articles | 2006
    Sasson SC; Zaunders J; Kelleher AD, 2006, 'The IL-7/IL-7 receptor axis: understanding its central role in T-cell homeostatis and the challenges facing its utilization as a novel therapy. 2006;7:1571-1582.', Current Drug Targets, 7, pp. 1571 - 1582
    Journal articles | 2006
    Sasson SC; Zaunders J; Zanetti G; King E; Merlin K; Smith DE; Stanley K; Cooper DA; Kelleher AD, 2006, 'Increased plasma interleukin-7 level correlates with decreased CD127 and increased CD132 extracellular expression on T cell subsets in patients with HIV-1 infection', Journal of Infectious Diseases, 193, pp. 505 - 514
    Journal articles | 2006
    Seddiki N; Santner-Nanan B; Martinson J; Zaunders J; Sasson SC; Landay A; Solomon MJ; Selby W; Alexander S; Nanan R; Kelleher AD; Fazekas de St Groth B; Solomon M, 2006, 'Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells', Journal of Experimental Medicine, 203, pp. 1693 - 1700, http://dx.doi.org/10.1084/jem.20060468
    Journal articles | 2006
    Zaunders J; Ip S; Munier CM; Munier M; Kaufmann D; Suzuki K; Brereton C; Seddiki N; Sasson SC; Koelsch KK; Landay A; Grey PA; Finlayson R; Kaldor JM; Rosenberg E; Walker BD; Fazekas de St Groth B; Cooper DA; Kelleher AD, 2006, 'Infection of CD127(+) (Interleukin-7 receptor+) CD4+ cells and overexpression of CTLA-4 are linked to loss of antigen-specific CD4 T cells during primary human immunodeficiency virus type 1 infection', Journal of Virology, 80, pp. 10162 - 10172
    Journal articles | 2005
    Sasson SC; Kelleher AD; Cooper DA, 2005, 'The modern ART of HIV infection management: Towards a tailored approach to maximize CD4 T cell reconstitution', Clinical Infectious Diseases, 41, pp. 373 - 375
  • Preprints | 2024
    Reardon B; Hsu J; Smith S; van der Linde R; Brown DA; Tegg E; Sasson SC, 2024, Anti-JOVI.1 antibody to detect clonal T cell populations: implementation into a diagnostic flow cytometry laboratory and correlation with clinical findings, http://dx.doi.org/10.1101/2024.03.20.24304408
    Preprints | 2023
    Dharan NJ; Sasson SC; Ahlenstiel G; Andersen CR; Bloch M; Buckland G; Hamad N; Han WM; Kelleher AD; Long GV; Matthews GV; Mina MM; Papot E; Petoumenos K; Swaminathan S; Withers B; Yun J; Polizzotto MN, 2023, Clinical and laboratory features of COVID-19 illness and outcomes in immunocompromised individuals during the first pandemic wave in Sydney, Australia, http://dx.doi.org/10.1101/2023.08.17.23293358
    Preprints | 2022
    Cromer D; Steain M; Reynaldi A; Schlub T; Sasson S; Kent S; Khoury D; Davenport MP, 2022, Neutralising antibodies predict protection from severe COVID-19, http://dx.doi.org/10.1101/2022.06.09.22275942
    Conference Papers | 2021
    Cheung V; Sasson S; Misheva M; Slevin S; Gupta T; Webb G; Walsh A; Simmons A; Quraishi N; Iqbal T; Middleton M; Fairfax B; Payne M; McCullagh J; Klenerman P; Brain O, 2021, 'P93 Faecal microbiota transplant for refractory checkpoint inhibitor immunotherapy-related colitis', in Posters, BMJ Publishing Group Ltd and British Society of Gastroenterology, pp. A89.1 - A89, presented at Abstracts of the BSG Campus, 21–29 January 2021, http://dx.doi.org/10.1136/gutjnl-2020-bsgcampus.168
    Conference Abstracts | 2020
    Cheung VT; Gupta T; Olsson-Brown AC; Subramanian S; Sasson SC; Heseltine J; Fryer E; Collantes-Bellido E; Sacco JJ; Pirmohamed M; Simmons A; Klenerman P; Fairfax BP; Payne MJ; Middleton MR; Brain O, 2020, 'IMMUNE CHECKPOINT INHIBITOR-RELATED COLITIS ASSESSMENT AND PROGNOSIS: CAN UCEIS, MAYO AND NANCY INDEX SCORING POINT THE WAY?', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, TX, Austin, Vol. 158, pp. S535 - S536, presented at Crohn's and Colitis Congress, TX, Austin, 23 January 2020 - 25 January 2020, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000540349501585&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2020
    Cheung VTF; Gupta T; Olsson-Brown A; Subramanian S; Sasson SC; Heseltine J; Fryer E; Collantes E; Sacco JJ; Pirmohamed M; Simmons A; Klenerman P; Fairfax BP; Payne MJ; Middleton MR; Brain O, 2020, 'Immune checkpoint inhibitor-related colitis assessment and prognosis: can inflammatory bowel disease scoring point the way?', in JOURNAL OF CROHNS & COLITIS, OXFORD UNIV PRESS, Vol. 14, pp. S286 - S288, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000518803401171&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2019
    Sasson SC; Cheung VTF; Gupta T; Zaunders JJ; Nahar K; Munier CM-L; Olsson-Brown A; Ahlenstiel G; Palendira U; Scolyer RA; Carlino MS; Long GV; Menzies AM; Kelleher A; Payne M; Fairfax B; Middleton MR; Klenerman P; Brain O, 2019, 'Tissue-based activation of mucosal-associated invariant T (MAIT) cells in combination ipilimumab and nivolumab checkpoint inhibitor (CI) colitis', in ANNALS OF ONCOLOGY, OXFORD UNIV PRESS, SPAIN, Barcelona, Vol. 30, pp. 530 - 530, presented at 44th Congress of the European-Society-for-Medical-Oncology (ESMO), SPAIN, Barcelona, 27 September 2019 - 01 October 2019, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000491295503349&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2019
    Sasson SC; Zaunders J; Nahar K; Munier C; Read SA; Ahlensteil G; Palendira U; Scolyer RA; Carlino M; Long GV; Menzies AM; Kelleher AD, 2019, 'Characterisation of peripheral blood mononuclear cells in patients with combination ipilimumab and nivolumab therapy-related colitis', in EUROPEAN JOURNAL OF CANCER, ELSEVIER SCI LTD, AUSTRIA, Vienna, Vol. 110, pp. S21 - S22, presented at 6tth International Cancer Immunotherapy Conference in Europe (ITOC), AUSTRIA, Vienna, 11 April 2019 - 13 April 2019, http://dx.doi.org/10.1016/j.ejca.2019.01.072
    Conference Abstracts | 2015
    Sasson SC; Davies S; Chan R; Davies L; Garsia R, 2015, 'IN GOOD CONSCIENCE', in INTERNAL MEDICINE JOURNAL, WILEY-BLACKWELL, Vol. 45, pp. 28 - 28, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000360834700088&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2015
    Sasson SC; McGill K; Weinholt L; Carr A; Brown DA; Kelleher AD; Breit SN; Sewell WA, 2015, 'COMPARISON OF THE FREELITE (TM) SERUM FREE LIGHT CHAIN (SFLC) ASSAY WITH SERUM AND URINE ELECTROPHORESIS/IMMUNOFIXATION AND THE N LATEX FLC ASSAY', in INTERNAL MEDICINE JOURNAL, WILEY-BLACKWELL, Vol. 45, pp. 24 - 24, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000360834700077&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

2024-2027 UNSW Scientia Fellowship (Renewed)

2022-2026 MRFF for Comparing Immunisation-boosting Regimens for COVID-19 for people Upon Initiation of immunosuppressive Therapies ("CIRCUIT" RCT) (CIA)

2022-2026 MRFF for Comparing Use of B cell depletion therapies to IVIg in CIDP ("CUBIC" Study) (CIG)

2022-2023 NSW Health Pathology Grant for Critical Illness, Infection and Immunology "CI3" Biobank

2021-22  NIH R21 Co-infection and Cancer

2020-23 UNSW Scientia Fellowship

2020       Kirby Institute Emerging Investigator Award

2020       Australian Intensive Care Foundation Grant

2019       University of Oxford Human Immunology Discovery Initiative Grant

2019       University of Oxford Medical Sciences Division Pump-Prime Grant

2019       Nanostring Autoimmunity Grant

2018-19 Oxford-Celgene Postdoctoral Fellowship

2013       SydPath Research Grant

2006       NHMRC Dora Lush (Biomedical) PhD Scholarship

2004       St Vincent's Hospital Centre for Immunology PhD Scholarship

 

Alum, immunologist and debut novelist—Inside UNSW Profile (2024)

Rising rates of Pregnancy-associated Cancer —The Conversation Article (2024)

$2.75M MRFF funding for CIRCUIT Study RCT (2022)—Kirby Institute Press Release 

"First Cancer Immunology Ideas Forum Takes place at UNSW" (2021) —Article in 'Oncology Republic'

"Immunocompromised: The forgotten people" (2021)—Interview on 'The Briefing' Podcast

COVID-19 Outcomes Registry Study for Immunosuppressed Patients in Australia (CORIA) Study (2020)—Press Release

My Research Supervision

  • Joshua Arena (PhD Student)
  • Tyler Shai-Hee (PhD Student)
  • Karthik Venkatesh (PhD Student)
  • Zong-Hong Zhang (PhD Student)