Dr Laura Bradfield

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Phone

93853078

E-mail

l.bradfield@unsw.edu.au

Publications

Books | 2017

Bradfield L; Morris R; Balleine BW, 2017, OCD as a Failure to Integrate Goal-Directed and Habitual Action Control, Pittenger C, (ed.), Oxford University Press, http://dx.doi.org/10.1093/med/9780190228163.003.0031
Book Chapters | 2017

Bradfield LA; Balleine BW, 2017, 'Chapter 6 The Learning and Motivational Processes Controlling Goal-Directed Action and Their Neural Bases', in Decision Neuroscience, Elsevier, pp. 71 - 80, http://dx.doi.org/10.1016/b978-0-12-805308-9.00006-3

Book Chapters | 2017

Bradfield LA; Balleine BW, 2017, 'The learning and motivational processes controlling goal-directed action and their neural bases', in Decision Neuroscience: An Integrative Perspective, pp. 71 - 80, http://dx.doi.org/10.1016/B978-0-12-805308-9.00006-3
Journal articles | 2025

Ganesan K; Ghorbanpour S; Kendall W; Broome ST; Gladding JM; Dhungana A; Abiero AR; Mahmoudi M; Castorina A; Kendig MD; Becchi S; Valova V; Cole L; Bradfield LA, 2025, 'Hippocampal neuroinflammation induced by lipopolysaccharide causes sex-specific disruptions in action selection, food approach memories, and neuronal activation', Brain, Behavior, and Immunity, 124, pp. 9 - 27, http://dx.doi.org/10.1016/j.bbi.2024.11.011

Journal articles | 2024

Bradfield LA; Becchi S; Kendig MD, 2024, 'Striatal Acetylcholine and Dopamine Interactions Produce Situationappropriate Action Selection', Current Neuropharmacology, 22, pp. 1491 - 1496, http://dx.doi.org/10.2174/1570159X21666230912093041

Journal articles | 2024

Rehn S; Gladding J; Bradfield L; Kendig M, 2024, 'Binge eating in adolescent rats', Obesity Research & Clinical Practice, 18, pp. S14 - S14, http://dx.doi.org/10.1016/j.orcp.2024.09.033

Journal articles | 2023

Becchi S; Chieng B; Bradfield LA; Capellán R; Leung BK; Balleine BW, 2023, 'Cognitive effects of thalamostriatal degeneration are ameliorated by normalizing striatal cholinergic activity', Science Advances, 9, http://dx.doi.org/10.1126/sciadv.ade8247

Journal articles | 2023

Dhungana A; Becchi S; Leake J; Morris G; Avgan N; Balleine BW; Vissel B; Bradfield LA, 2023, 'Goal-Directed Action Is Initially Impaired in a hAPP-J20 Mouse Model of Alzheimer’s Disease', eNeuro, 10, http://dx.doi.org/10.1523/ENEURO.0363-22.2023

Journal articles | 2023

Gladding JM; Bradfield LA; Kendig MD, 2023, 'Diet and obesity effects on cue-driven food-seeking: insights from studies of Pavlovian-instrumental transfer in rodents and humans', Frontiers in Behavioral Neuroscience, 17, http://dx.doi.org/10.3389/fnbeh.2023.1199887

Journal articles | 2023

Piper JA; Al Hammouri N; Jansen MI; Rodgers KJ; Musumeci G; Dhungana A; Ghorbanpour SM; Bradfield LA; Castorina A, 2023, 'L-Proline Prevents Endoplasmic Reticulum Stress in Microglial Cells Exposed to L-azetidine-2-carboxylic Acid', Molecules, 28, http://dx.doi.org/10.3390/molecules28124808

Journal articles | 2022

Abiero AR; Ali Z; Vissel B; Bradfield LA, 2022, 'Outcome-selective reinstatement is predominantly context-independent, and associated with c-Fos activation in the posterior dorsomedial striatum', Neurobiology of Learning and Memory, 187, http://dx.doi.org/10.1016/j.nlm.2021.107556

Journal articles | 2022

Kendig MD; Bradfield LA, 2022, 'Association learning: Dopamine and the formation of backward associations', Current Biology, 32, pp. R769 - R771, http://dx.doi.org/10.1016/j.cub.2022.06.007

Journal articles | 2022

Khoo SY-S; Kendig MD; Bradfield LA, 2022, 'Animal research is saving lives, but funding is needed to improve welfare: Submission to the New South Wales parliamentary inquiry', Neuroanatomy and Behaviour, 4, pp. e45 - e45, http://dx.doi.org/10.35430/nab.2022.e45

Journal articles | 2022

Watson P; O'Callaghan C; Perkes I; Bradfield L; Turner K, 2022, 'Making habits measurable beyond what they are not: A focus on associative dual-process models', Neuroscience and Biobehavioral Reviews, 142, http://dx.doi.org/10.1016/j.neubiorev.2022.104869

Journal articles | 2021

Abiero AR; Bradfield LA, 2021, 'The contextual regulation of goal-directed actions', Current Opinion in Behavioral Sciences, 41, pp. 57 - 62, http://dx.doi.org/10.1016/j.cobeha.2021.03.022

Journal articles | 2021

Bradfield L; Balleine B, 2021, 'Editorial overview: Value-based decision making: control, value, and context in action', Current Opinion in Behavioral Sciences, 41, pp. iii - vi, http://dx.doi.org/10.1016/j.cobeha.2021.09.003

Journal articles | 2021

Bradfield LA; Iordanova MD, 2021, 'Threat perception: Fear and the retrorubal field', Current Biology, 31, pp. R469 - R471, http://dx.doi.org/10.1016/j.cub.2021.03.065

Journal articles | 2021

Manning EE; Bradfield LA; Iordanova MD, 2021, 'Adaptive behaviour under conflict: Deconstructing extinction, reversal, and active avoidance learning', Neuroscience and Biobehavioral Reviews, 120, pp. 526 - 536, http://dx.doi.org/10.1016/j.neubiorev.2020.09.030

Journal articles | 2021

Stayte S; Dhungana A; Vissel B; Bradfield LA, 2021, 'Parafascicular Thalamic and Orbitofrontal Cortical Inputs to Striatum Represent States for Goal-Directed Action Selection', Frontiers in Behavioral Neuroscience, 15, http://dx.doi.org/10.3389/fnbeh.2021.655029

Journal articles | 2021

Turner KM; Balleine BW; Bradfield LA, 2021, 'Does disrupting the orbitofrontal cortex alter sensitivity to punishment? A potential mechanism of compulsivity.', Behavioral Neuroscience, 135, pp. 174 - 181, http://dx.doi.org/10.1037/bne0000443

Journal articles | 2021

Turner KM; Ganesan K; Bradfield LA, 2021, 'Evidence That Compulsive Reward Seeking Has Been Hiding in the Central Dorsal Striatum', Biological Psychiatry, 90, pp. 800 - 802, http://dx.doi.org/10.1016/j.biopsych.2021.10.003

Journal articles | 2020

Bradfield LA; Hart G, 2020, 'Rodent medial and lateral orbitofrontal cortices represent unique components of cognitive maps of task space', Neuroscience and Biobehavioral Reviews, 108, pp. 287 - 294, http://dx.doi.org/10.1016/j.neubiorev.2019.11.009

Journal articles | 2020

Bradfield LA; Leung BK; Boldt S; Liang S; Balleine BW, 2020, 'Goal-directed actions transiently depend on dorsal hippocampus', Nature Neuroscience, 23, pp. 1194 - 1197, http://dx.doi.org/10.1038/s41593-020-0693-8

Journal articles | 2020

Jean-Richard-dit-Bressel P; Ma C; Bradfield L; Killcross S; McNally G, 2020, 'Punishment insensitivity emerges from impaired contingency detection, not aversion insensitivity or reward dominance', eLife, http://dx.doi.org/10.7554/eLife.52765

Journal articles | 2020

Ma C; Jean-Richard-Dit-Bressel P; Roughley S; Vissel B; Balleine BW; Killcross S; Bradfield LA, 2020, 'Medial Orbitofrontal Cortex Regulates Instrumental Conditioned Punishment, but not Pavlovian Conditioned Fear.', Cereb Cortex Commun, 1, pp. tgaa039, http://dx.doi.org/10.1093/texcom/tgaa039

Journal articles | 2020

Ma C; Jean-Richard-dit-Bressel P; Roughley S; Vissel B; Balleine B; Killcross S; Bradfield L, 2020, 'Medial Orbitofrontal Cortex Regulates Instrumental Conditioned Punishment, but not Pavlovian Conditioned Fear', , http://dx.doi.org/10.1101/2020.05.12.092205

Journal articles | 2020

Turner K; Balleine B; Bradfield L, 2020, 'Does disrupting the Orbitofrontal Cortex alter sensitivity to punishment? A potential mechanism of compulsivity', , http://dx.doi.org/10.31234/osf.io/cwvmx

Journal articles | 2019

Bradfield L; Leung B; Boldt S; Balleine B, 2019, 'Goal-directed action transiently depends on action space', , http://dx.doi.org/10.1101/783308

Journal articles | 2019

Jean-Richard-dit-Bressel P; Ma C; Bradfield LA; Killcross S; McNally GP, 2019, 'Punishment insensitivity emerges from impaired contingency detection, not aversion insensitivity or reward dominance', eLife, 8, pp. e52765, http://dx.doi.org/10.7554/eLife.52765

Journal articles | 2018

Bradfield LA; Hart G; Balleine BW, 2018, 'Inferring action-dependent outcome representations depends on anterior but not posterior medial orbitofrontal cortex', Neurobiology of Learning and Memory, 155, pp. 463 - 473, http://dx.doi.org/10.1016/j.nlm.2018.09.008

Journal articles | 2018

Bradfield LA; Matamales M; Bertran-Gonzalez J, 2018, 'The Thalamostriatal Pathway and the Hierarchical Control of Action', Neuron, 100, pp. 521 - 523, http://dx.doi.org/10.1016/j.neuron.2018.10.041

Journal articles | 2018

Hart G; Bradfield LA; Balleine BW, 2018, 'Prefrontal corticostriatal disconnection blocks the acquisition of goal-directed action', Journal of Neuroscience, 38, pp. 1311 - 1322, http://dx.doi.org/10.1523/JNEUROSCI.2850-17.2017

Journal articles | 2018

Hart G; Bradfield LA; Fok SY; Chieng B; Balleine BW, 2018, 'The Bilateral Prefronto-striatal Pathway Is Necessary for Learning New Goal-Directed Actions', Current Biology, 28, pp. 2218 - 2229.e7, http://dx.doi.org/10.1016/j.cub.2018.05.028

Journal articles | 2017

Bradfield LA; Balleine BW, 2017, 'Thalamic control of dorsomedial striatum regulates internal state to guide goal-directed action selection', Journal of Neuroscience, 37, pp. 3721 - 3733, http://dx.doi.org/10.1523/JNEUROSCI.3860-16.2017

Journal articles | 2015

Bradfield LA; Dezfouli A; Van Holstein M; Chieng B; Balleine BW, 2015, 'Medial Orbitofrontal Cortex Mediates Outcome Retrieval in Partially Observable Task Situations', Neuron, 88, pp. 1268 - 1280, http://dx.doi.org/10.1016/j.neuron.2015.10.044

Journal articles | 2015

Parkes SL; Bradfield LA; Balleine BW, 2015, 'Interaction of insular cortex and ventral striatum mediates the effect of incentive memory on choice between goal-directed actions', Journal of Neuroscience, 35, pp. 6464 - 6471, http://dx.doi.org/10.1523/JNEUROSCI.4153-14.2015

Journal articles | 2013

Bradfield LA; Balleine BW, 2013, 'Hierarchical and binary associations compete for behavioral control during instrumental biconditional discrimination', Journal of Experimental Psychology: Animal Behavior Processes, 39, pp. 2 - 13, http://dx.doi.org/10.1037/a0030941

Journal articles | 2013

Bradfield LA; Bertran-Gonzalez J; Chieng B; Balleine BW, 2013, 'The Thalamostriatal Pathway and Cholinergic Control of Goal-Directed Action: Interlacing New with Existing Learning in the Striatum', Neuron, 79, pp. 153 - 166, http://dx.doi.org/10.1016/j.neuron.2013.04.039

Journal articles | 2013

Bradfield LA; Hart G; Balleine BW, 2013, 'The role of the anterior, mediodorsal, and parafascicular thalamus in instrumental conditioning', FRONTIERS IN SYSTEMS NEUROSCIENCE, 7, http://dx.doi.org/10.3389/fus4s.2013.00051

Journal articles | 2013

Bradfield LA; Hart G; Balleine BW, 2013, 'The role of the anterior, mediodorsal, and parafascicular thalamus in instrumental conditioning', Frontiers in Systems Neuroscience, 7, http://dx.doi.org/10.3389/fnsys.2013.00051

Journal articles | 2010

Bradfield LA; McNally GP, 2010, 'The role of nucleus accumbens shell in learning about neutral versus excitatory stimuli during Pavlovian fear conditioning', Learning and Memory, 17, pp. 337 - 343, http://dx.doi.org/10.1101/lm.1798810

Journal articles | 2008

Bradfield LA; Mcnally GP, 2008, 'Unblocking in Pavlovian fear conditioning', Journal of Experimental Psychology - Animal Behavior Processes, 34, pp. 256 - 265, http://dx.doi.org/10.1037/0097-7403.34.2.256
Preprints | 2024

Abiero AR; Gladding JM; Iredale JA; Drury HR; Manning EE; Dayas CV; Dhungana A; Ganesan K; Turner K; Becchi S; Kendig MD; Nolan C; Balleine B; Castorina A; Cole L; Clemens KJ; Bradfield LA, 2024, Neuroinflammation in the dorsomedial striatum causes excessive goal-directed action control by disrupting homeostatic astrocyte function, http://dx.doi.org/10.1101/2024.10.24.620154

Preprints | 2024

Ganesan K; Ghorbanpour S; Kendall W; Broome ST; Gladding JM; Dhungana A; Abiero AR; Mahmoudi M; Castorina A; Kendig MD; Becchi S; Valova V; Cole L; Bradfield LA, 2024, Hippocampal neuroinflammation causes sex-specific disruptions in action selection, food approach memories, and neuronal activation, http://dx.doi.org/10.1101/2024.05.19.594460

Preprints | 2022

Becchi S; Chieng B; Bradfield L; Capellán R; Leung B; Balleine B, 2022, Cognitive effects of thalamostriatal degeneration are ameliorated by normalizing striatal cholinergic activity, http://dx.doi.org/10.1101/2022.08.25.505358

Preprints | 2022

Dhungana A; Becchi S; Leake J; Morris G; Avgan N; Balleine B; Vissel B; Bradfield L, 2022, Goal-directed action is transiently impaired in an hAPP-J20 mouse model of Alzheimer’s disease, and in aging male mice regardless of genotype, http://dx.doi.org/10.1101/2022.07.25.501480

Preprints | 2022

Watson P; O'Callaghan C; Perkes I; Bradfield L; Turner K, 2022, Making habits measurable beyond what they are not: a focus on associative dual-process models, , http://dx.doi.org/10.31234/osf.io/7m6c8

Preprints | 2021

Abiero A; Ali Z; Vissel B; Bradfield L, 2021, Outcome-selective reinstatement is predominantly context-independent, and associated with c-Fos activation in the posterior dorsomedial striatum, http://dx.doi.org/10.1101/2021.07.28.454246

Preprints | 2019

Bradfield L; Hart G, 2019, Medial and lateral orbitofrontal cortices represent unique components of cognitive maps of task space, http://dx.doi.org/10.31234/osf.io/tk5gn

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Dr Laura Bradfield