Dr Lana Ly

Dr Lana Ly

Associate Lecturer
  • PhD Biochemistry and Molecular Genetics, UNSW Sydney
  • BAdvSci(Hons) Molecular and Cell Biology, UNSW Sydney

 

 

Science
School of Biotech & Biomolecular Science

Lana completed a Bachelors of Advanced Science (Honours) degree at UNSW Sydney, majoring in Molecular and Cell Biology. In 2017, she continued on to complete her PhD in Biochemistry and Molecular Genetics in the Crossley Lab at UNSW Sydney under the supervision of A/Prof. Kate Quinlan and Prof. Merlin Crossley. After submitting her PhD in May 2021, Lana continued on as a postdoctoral research associate until the end of the year. Her research involved investigating the DNA binding mechanisms of the transcription factor ZBTB7A/LRF as a therapeutic to treat red blood cell disorders such as sickle cell anaemia and beta-thalassemia.

Lana has been actively involved in sessional undergraduate teaching as a demonstrator/tutor in the School of Biotechnology and Biomolecular Sciences (BABS) since the commencement of her PhD. In 2022, Lana transitioned to a full-time, education-focussed Associate Lecturer position in the School of BABS.

  • Journal articles | 2022
    Ly LC; Yang Y; Li F; Crossley M; Shi Y; Quinlan KGR, 2022, 'Protocols for protein-DNA binding analysis of a zinc finger transcription factor bound to its cognate promoter', STAR protocols, 3, pp. 101598, http://dx.doi.org/10.1016/j.xpro.2022.101598
    Journal articles | 2022
    Topfer SK; Feng R; Huang P; Ly LC; Martyn GE; Blobel GA; Weiss MJ; Quinlan KGR; Crossley M, 2022, 'Disrupting the adult globin promoter alleviates promoter competition and reactivates fetal globin gene expression', Blood, 139, pp. 2107 - 2118, http://dx.doi.org/10.1182/blood.2021014205
    Journal articles | 2021
    Lan X; Ren R; Feng R; Ly LC; Lan Y; Zhang Z; Aboreden N; Qin K; Horton JR; Grevet JD; Mayuranathan T; Abdulmalik O; Keller CA; Giardine B; Hardison RC; Crossley M; Weiss MJ; Cheng X; Shi J; Blobel GA, 2021, 'ZNF410 Uniquely Activates the NuRD Component CHD4 to Silence Fetal Hemoglobin Expression', Molecular Cell, 81, pp. 239 - 254.e8, http://dx.doi.org/10.1016/j.molcel.2020.11.006
    Journal articles | 2021
    Yang Y; Ren R; Ly LC; Horton JR; Li F; Quinlan KGR; Crossley M; Shi Y; Cheng X, 2021, 'Structural basis for human ZBTB7A action at the fetal globin promoter', Cell Reports, 36, http://dx.doi.org/10.1016/j.celrep.2021.109759
    Journal articles | 2020
    Lan X; Ren R; Feng R; Ly LC; Lan Y; Zhang Z; Aboreden N; Qin K; Horton JR; Grevet JD; Mayuranathan T; Abdulmalik O; Keller CA; Giardine B; Hardison RC; Crossley M; Weiss MJ; Cheng X; Shi J; Blobel GA, 2020, 'ZNF410 Uniquely Activates the NuRD Component CHD4 to Silence Fetal Hemoglobin Expression', BLOOD, 136, http://dx.doi.org/10.1182/blood-2020-137564
  • Preprints | 2024
    Xu S; Ren R; Peng C; Lu H; Ly LC; Crossley M; Xu B; Cheng X; Blobel GA; Lan X, 2024, Mechanistic dissection of theCHD4enhancers reveals cooperative functions among the homotypic ZNF410 clustered motifs, http://dx.doi.org/10.1101/2024.02.24.581901
    Preprints | 2020
    Lan X; Ren R; Feng R; Ly LC; Lan Y; Zhang Z; Aboreden N; Qin K; Horton JR; Grevet JD; Mayuranathan T; Abdulmalik O; Keller CA; Giardine B; Hardison RC; Crossley M; Weiss MJ; Cheng X; Shi J; Blobel GA, 2020, ZNF410 uniquely activates the NuRD component CHD4 to silence fetal hemoglobin expression, http://dx.doi.org/10.1101/2020.08.31.274324

  • 2023:

    • BABS Titans of Teaching Award for Runner-Up Best Lecturer in a Small Course (BABS3121 T1, 2023) (determined by myExperience student survey data)

    • BABS Titans of Teaching Award for Best Lecturer in a Large Course (BIOC2201 T3, 2022) (determined by myExperience student survey data)

    • BABS Titans of Teaching Award for Best Large Course (BIOC2201 T3, 2022) (determined by myExperience student survey data)

  • 2022:

    • BABS Titans of Teaching Award for Runner-Up Best Lecturer in a Large Course (BIOC2101 T2, 2022) (determined by myExperience student survey data)

    • BABS Titans of Teaching Award for Best Lecturer in a Small Course (BABS3121 T1, 2022) (determined by myExperience student survey data)

    • BABS Titans of Teaching Award for Runner-Up Best Small Course (BABS3121 T1, 2022) (determined by myExperience student survey data)

    • BABS Titans of Teaching Award for Best Lecturer in a Large Course (BIOC2201 T3, 2021) (determined by myExperience student survey data)

  • 2021: Associate Fellow of the Higher Education Academy (AFHEA)

  • 2021: UNSW Award for Teaching for Outstanding Contributions to Student Learning (sessional category)

  • 2021: UNSW Scientia Education Academy Exemplary Teaching Practice Award in the category 'Challenging and Supporting Students to Engage in Active Learning'

  • 2020: Dean of Science Staff Excellence Award (for excellence in education)

  • 2019: UNSW Arc Postgraduate Council Outstanding Research Student Award

  • 2018: Second-place prize winner in the UNSW Science Postgraduate Research competition

My Teaching

I currently teach across second- and third-year biochemistry and molecular biology subjects within BABS. Courses I currently teach are: