Dr Kate Michie

Dr Kate Michie

Senior Lecturer

Education

  • BSc Hons (1st Class) (The University of Sydney). 1998
  • PhD (The University of Sydney) 2004
Research & Enterprise
Structural Biology Facility

Biography

Dr Kate Michie is Chief Scientist of the Structural Biology Facility (MWAC) and a Senior lecturer in BABS. She is a molecular biologist/biochemist with special interests in structural biology. She currently leads a specialist compute team supporting AI/Deep Learning methods for UNSW researchers in structural biology.

Kate completed her doctoral degree at the University of Sydney under the supervision of Dr Liz Harry and Professor Gerry Wake, working in the field of bacterial c...

 International

ASIAN OFFICE OF AEROSPACE R&D 21IOA019. Awarded Sep 2021 for funding 2021-2023.

MEDICAL RESEARCH FUTURE FUND (MRFF) APP2016906. Awarded April 2022.

 

2007    Named ‘Rising Talent’ and short-listed for Women’s Forum 3rd Ed, Deauville, France.

2006    Marie Curie International Fellowship Funded by 6th European Commission Framework

2005   UNESCO L'Oreal International Fellowship for Women in Science 7th edition of the L’ORÉAL-UNESCO FOR WOMEN IN SCIENCE (Life sciences), Funded by UNESCO and L’Oreal.

We want to understand how biology uses proteins to control the shape of membranes. In particular we focus on the proteins essential to the processes of cell division and building cell surface structures such as villi and vesicles. The proteins involved in these processes interact with themselves and with the membrane to bend and shape it, and to tether other proteins to it. The types of proteins involved arise in all the domains of life— archaea, bacteria and eukaryotes, and, maybe not surprisingly, are often carried out by related proteins.

We focus on understanding structurally the proteins that carry out these tasks. We use X-ray crystallography, cryo-electron microscopy and a range of protein and biophysical experiments to probe our targets.

 

CURRENT RESEARCH ACTIVITIES

  • Dynamin-like Proteins in Bacteria

  • Tubulin-like proteins in Bacteria and Archaea (collaboration with Dr Brendan Burns)

  • Ezrin/Moesin and Merlin and the membrane in humans (Jointly supervised with Prof Curmi)

  • Understanding mutations in clinical setting (collaboration with Dr Emily Oates)

  • Alphafold2- implementation and it's roles in integrative structural biology

 

My Research Supervision

PhDs in Physics

PhDs in BABS

Honours in BABS

My Teaching

Currently teaching into:

BABS2011Current Trends in Biotechnology