Dr Jonathan Brett

Senior Research Fellow

MBBS (hons) GCertClinTox FRACP FAChAM PhD

Medicine & Health

School of Population Health

I am a senior staff specialist in clinical pharmacology, toxicology and addiction medicine at St. Vincent's Hospital and a clinical toxicologist with the NSW Poisons Centre. I am a conjoint Associate Professor at St. Vincent's Clinical School and a Senior Research Fellow with the Medicines and Health Intelligence Unit at the School of Population Health, UNSW. My research areas span neuropsychopharmacology, drugs of abuse and medicines use in pregnancy. I have a PhD in pharmacoepidemiology a...

Phone

+61283822304

E-mail

j.brett@unsw.edu.au

Location

Medicines and Health Intelligence, School of Population Health, UNSW Sydney St Vincent’s Clinical School, UNSW Medicine, UNSW Sydney Department of Clinical Pharmacology & Toxicology Therapeutics Centre, Level 2 Xavier Building St Vincent’s Hospital Sydney 390 Victoria Street DARLINGHURST NSW 2010 AUSTRALIA

Publications
Grants
Awards
Research Activities
Teaching and Supervision

Book Chapters | 2024

Brett J; Zoega H, 2024, 'Drug utilization research on selected psychotropics', in Drug Utilization Research: Methods and Applications: Second Edition, pp. 363 - 372, http://dx.doi.org/10.1002/9781119911685.ch35

Book Chapters | 2014

Roberts DM; Brett J, 2014, 'Clinical management of acute OP pesticide poisoning', in Basic and Clinical Toxicology of Organophosphorus Compounds, pp. 141 - 175, http://dx.doi.org/10.1007/978-1-4471-5625-3_6
Journal articles | 2025

Brett J; Cesta CE; Gillies MB; Bateman BT; Chan AYL; Cheng MCY; Cho Y; Choi EY; Cohen JM; Donald S; Furu K; Gissler M; Gomes T; Havard A; Hernandez-Diaz S; Hsieh MHC; Huybrechts KF; Karlsson P; Kelty E; Lai ECC; Ledlie S; Wang T; Leinonen MK; Parkin L; Reutfors J; Shin JY; Su CTT; Varney B; Wong ICK; Man KKC; Zoega H, 2025, 'Global trends in analgesic opioid use in pregnancy: A retrospective cohort study', Anesthesiology, http://dx.doi.org/10.1097/ALN.0000000000005418

Journal articles | 2025

Fletcher K; Ezard N; Siefried KJ; MacDonald H; Acheson L; Bedi G; Guerin A; Knock E; Millard M; May R; Brett J; Doumany J; Morgan C; Clifford B, 2025, 'Protocol of an open-label safety and feasibility pilot study of ketamine-assisted psychotherapy for methamphetamine use disorder (the KAPPA trial)', BMJ open, 15, pp. e092504, http://dx.doi.org/10.1136/bmjopen-2024-092504

Journal articles | 2025

Siefried KJ; Acheson L; Clifford B; Moller C; Brett J; Christmass M; Dunlop AJ; Haber PS; Jutras-Aswad D; Lintzeris N; Morley K; Shoptaw S; Trivedi MH; Ezard N, 2025, 'Trial protocol of an open-label pilot study of oral naltrexone-bupropion combination pharmacotherapy for the treatment of methamphetamine use disorder (the NABU trial)', BMJ open, 15, pp. e092032, http://dx.doi.org/10.1136/bmjopen-2024-092032

Journal articles | 2024

Acheson L; Gordon C; McKetin R; Brett J; Christmass M; Rodgers C; Lintzeris N; Dunlop A; Farrell M; Shoptaw S; Ezard N; Siefried K, 2024, 'OBJECTIVE AND SUBJECTIVE SLEEP DURING LISDEXAMFETAMINE TREATMENT OF ACUTE METHAMPHETAMINE WITHDRAWAL: NEW MEASUREMENT PARADIGM', Drug and Alcohol Dependence, 260, pp. 110067 - 110067, http://dx.doi.org/10.1016/j.drugalcdep.2023.110067

Journal articles | 2024

Acheson LS; Clay S; McKetin R; Lintzeris N; Dunlop A; Brett J; Christmass M; Rodgers C; Shoptaw S; Farrell M; Ezard N; Siefried KJ, 2024, 'Participant experiences in a pilot study for methamphetamine withdrawal treatment: Implications for retention', International Journal of Drug Policy, 126, http://dx.doi.org/10.1016/j.drugpo.2024.104383

Journal articles | 2024

Acheson LS; Gordon C; Mcketin R; Brett J; Christmass M; Rodgers C; Lintzeris N; Dunlop A; Farrell M; Shoptaw S; Ezard N; Siefried KJ, 2024, 'Measuring Objective and Subjective Sleep during Lisdexamfetamine Treatment of Acute Methamphetamine Withdrawal: A Feasibility Study', European Addiction Research, 30, pp. 121 - 125, http://dx.doi.org/10.1159/000536328

Journal articles | 2024

Brett J; Knock E; Watson K; Albert S; Siefried KJ; Guss J, 2024, 'Psilocybin-assisted psychotherapy for methamphetamine dependence: a case report involving daily methamphetamine use', Frontiers in Psychiatry, 15, http://dx.doi.org/10.3389/fpsyt.2024.1490907

Journal articles | 2024

Cairns R; Noghrehchi F; Raubenheimer JE; Chitty KM; Isbister GK; Chiew AL; Brett J; Dawson AH; Brown JA; Buckley NA, 2024, 'Poisoning and envenomation linkage to evaluate outcomes and clinical variation in Australia (PAVLOVA): a longitudinal data-linkage cohort of acute poisonings, envenomations, and adverse drug reactions in New South Wales, Australia, 2011–2020', Clinical Toxicology, 62, pp. 615 - 624, http://dx.doi.org/10.1080/15563650.2024.2398119

Journal articles | 2024

Camacho X; Schaffer AL; Brett J; Pratt N; Buckley NA; Henry D; Pearson SA, 2024, 'Quality use of publicly subsidised tapentadol in Australia: a population-based analysis', Internal Medicine Journal, 54, pp. 941 - 950, http://dx.doi.org/10.1111/imj.16335

Journal articles | 2024

Carland JE; Carland DJ; Brett J; Stocker SL; Roberts DM; Day RO; Laba TL, 2024, 'Economic evaluations of therapeutic drug monitoring interventions in acute hospital-based settings: A systematic review', British Journal of Clinical Pharmacology, 90, pp. 2038 - 2066, http://dx.doi.org/10.1111/bcp.16164

Journal articles | 2024

Carroll A; Bayes A; Montebello M; Brett J; Arunogiri S; Saunders JB; Loo CK, 2024, 'Drug dependence and prescribing ketamine for treatment-resistant depression in Australia and New Zealand', Australian and New Zealand Journal of Psychiatry, 58, pp. 831 - 838, http://dx.doi.org/10.1177/00048674241242315

Journal articles | 2024

Harris O; Siefried KJ; Chiew A; Jamshidi N; Chung DT; Moore N; Nic Ionmhain U; Roberts DM; Ezard N; Brett J, 2024, 'Trends in reported GHB-related presentations to Sydney emergency departments between 2012 and 2021', EMA - Emergency Medicine Australasia, 36, pp. 604 - 608, http://dx.doi.org/10.1111/1742-6723.14402

Journal articles | 2024

Koch FC; Olivier J; Brett J; Buckley NA; Gisev N; Pearson S; Daniels B, 2024, 'The impact of tightened prescribing restrictions for PBS-subsidised opioid medicines and the introduction of half-pack sizes, Australia, 2020–21: an interrupted time series analysis', Medical Journal of Australia, 220, pp. 315 - 322, http://dx.doi.org/10.5694/mja2.52257

Journal articles | 2024

Page R; Jauncey M; Brett J; Wood W; Roxburgh A, 2024, 'The role of on-site drug analysis within supervised injecting facilities: A case presentation of an adverse event highlighting need', Drug and Alcohol Review, 43, pp. 1592 - 1596, http://dx.doi.org/10.1111/dar.13909

Journal articles | 2024

Schulz M; Coleshill MJ; Day RO; Wright DFB; Brett J; Briggs NE; Aung E, 2024, 'Estimation of adherence to urate-lowering therapy in people living with gout using Australia's Pharmaceutical Benefits Scheme and patient-reported dosing', British Journal of Clinical Pharmacology, 90, pp. 1322 - 1332, http://dx.doi.org/10.1111/bcp.16016

Journal articles | 2024

Solaja I; Haldane K; Mason N; Weiss B; Xu X; Xu M; Nikolin S; Jayasena T; Millard M; Brett J; Bayes A; Loo CK; Martin DM, 2024, 'Who are you after psychedelics? A systematic review and a meta-analysis of the magnitude of long-term effects of serotonergic psychedelics on cognition/creativity, emotional processing and personality', Neuroscience and Biobehavioral Reviews, 158, http://dx.doi.org/10.1016/j.neubiorev.2024.105570

Journal articles | 2024

Varney B; Brett J; Zoega H; Gillies MB; Powell M; Bateman BT; Shand AW; Pearson SA; Havard A, 2024, 'Opioid analgesic exposure during the first trimester of pregnancy and the risk of major congenital malformations in infants: a systematic review and meta-analysis^†', Anaesthesia, 79, pp. 967 - 977, http://dx.doi.org/10.1111/anae.16307

Journal articles | 2024

Wardle F; Piatkowski T; Clifford S; Peacock A; Dietze P; Lim M; Douglass C; Hill P; Moore S; Miller M; Brett J; Wright CJC, 2024, 'Safe beats down under: investigating the support of drug checking at a regional festival in the Northern Territory, Australia', Drugs: Education, Prevention and Policy, http://dx.doi.org/10.1080/09687637.2024.2330938

Journal articles | 2024

Wilkes R; Roberts DM; Liknaitzky P; Brett J, 2024, 'The psychedelic call: analysis of Australian Poisons Information Centre calls associated with classic psychedelics', Clinical Toxicology, 62, pp. 242 - 247, http://dx.doi.org/10.1080/15563650.2024.2346612

Journal articles | 2024

Zhou F; Khushi M; Brett J; Uddin S, 2024, 'Graph neural network-based subgraph analysis for predicting adverse drug events', Computers in Biology and Medicine, 183, http://dx.doi.org/10.1016/j.compbiomed.2024.109282

Journal articles | 2023

Brett J; Bahceci D; Lipworth W; Liknaitzky P; Day RO; Rodgers A, 2023, 'Can old drugs learn new tricks? Achieving registration and public subsidy listing for off-patent medicines with novel therapeutic applications', Internal Medicine Journal, 53, pp. 1284 - 1287, http://dx.doi.org/10.1111/imj.16159

Journal articles | 2023

Brett J; Gillies MB; Buckley NA; Pearson SA; Zoega H, 2023, 'Patterns of suboptimal antipsychotic use and misuse in Australia: What can routinely collected data tell us?', British Journal of Clinical Pharmacology, 89, pp. 3411 - 3420, http://dx.doi.org/10.1111/bcp.15821

Journal articles | 2023

Brett J; Knock E; Korthuis PT; Liknaitzky P; Murnane KS; Nicholas CR; Patterson JC; Stauffer CS, 2023, 'Exploring psilocybin-assisted psychotherapy in the treatment of methamphetamine use disorder', Frontiers in Psychiatry, 14, http://dx.doi.org/10.3389/fpsyt.2023.1123424

Journal articles | 2023

Bruno C; Havard A; Gillies MB; Coghill D; Brett J; Guastella AJ; Pearson SA; Zoega H, 2023, 'Patterns of attention deficit hyperactivity disorder medicine use in the era of new non-stimulant medicines: A population-based study among Australian children and adults (2013–2020)', Australian and New Zealand Journal of Psychiatry, 57, pp. 675 - 685, http://dx.doi.org/10.1177/00048674221114782

Journal articles | 2023

Bruno C; Zoega H; Gillies MB; Havard A; Coghill D; Pearson SA; Brett J, 2023, 'Expanded access to publicly subsidised lisdexamfetamine treatment for adults with attention-deficit/hyperactivity disorder: An interrupted time-series analysis', Australian and New Zealand Journal of Psychiatry, 57, pp. 1073 - 1076, http://dx.doi.org/10.1177/00048674231170556

Journal articles | 2023

Carland JE; Stacy AE; Schaffer AL; Day RO; Brett J; Reuter SE; Stocker SL, 2023, 'Blood, dose recommendation reports and phone calls: Experiences of a therapeutic drug monitoring advisory service for vancomycin', British Journal of Clinical Pharmacology, 89, pp. 1896 - 1902, http://dx.doi.org/10.1111/bcp.15668

Journal articles | 2023

Freeman G; Siefried KJ; Roberts DM; Rodgers C; Nic Ionmhain U; Ramanathan J; Ezard N; Brett J, 2023, 'Phenobarbital to manage severe gamma-hydroxybutyrate withdrawal: A case series', Drug and Alcohol Review, 42, pp. 27 - 32, http://dx.doi.org/10.1111/dar.13556

Journal articles | 2023

Freestone J; Ezard N; Bourne A; Brett J; Roberts DM; Hammoud M; Nedanoski A; Prestage G; Siefried KJ, 2023, 'Understandings, attitudes, practices and responses to GHB overdose among GHB consumers', Harm Reduction Journal, 20, pp. 121, http://dx.doi.org/10.1186/s12954-023-00857-z

Journal articles | 2023

Siefried KJ; Freeman G; Roberts DM; Lindsey R; Rodgers C; Ezard N; Brett J, 2023, 'Inpatient GHB withdrawal management in an inner-city hospital in Sydney, Australia: a retrospective medical record review', Psychopharmacology, 240, pp. 127 - 135, http://dx.doi.org/10.1007/s00213-022-06283-6

Journal articles | 2023

Yang JJ; Brett J; Sordo A; Reuter SE; Stocker SL; Day RO; Roberts DM; Carland JE, 2023, 'The Influence of a Therapeutic Drug Monitoring Service on Vancomycin-Associated Nephrotoxicity', Journal of Clinical Pharmacology, 64, pp. 19 - 29, http://dx.doi.org/10.1002/jcph.2363

Journal articles | 2022

Acheson LS; Ezard N; Lintzeris N; Dunlop A; Brett J; Rodgers C; Gill A; Christmass M; McKetin R; Farrell M; Shoptaw S; Siefried KJ, 2022, 'Lisdexamfetamine for the treatment of acute methamphetamine withdrawal: A pilot feasibility and safety trial', Drug and Alcohol Dependence, 241, pp. 109692, http://dx.doi.org/10.1016/j.drugalcdep.2022.109692

Journal articles | 2022

Acheson LS; Ezard N; Lintzeris N; Dunlop A; Brett J; Rodgers C; Gill A; Christmass M; McKetin R; Farrell M; Shoptaw S; Siefried KJ, 2022, 'Trial protocol of an open label pilot study of lisdexamfetamine for the treatment of acute methamphetamine withdrawal', PLoS ONE, 17, pp. e0275371, http://dx.doi.org/10.1371/journal.pone.0275371

Journal articles | 2022

Black E; Monds LA; Chan B; Brett J; Hutton JE; Acheson L; Penm J; Harding S; Strumpman D; Demirkol A; Lintzeris N, 2022, 'Overdose and take-home naloxone in emergency settings: A pilot study examining feasibility of delivering brief interventions addressing overdose prevention with ‘take-home naloxone’ in emergency departments', EMA - Emergency Medicine Australasia, 34, pp. 509 - 518, http://dx.doi.org/10.1111/1742-6723.13925

Journal articles | 2022

Brett J; Siefried KJ; Healey A; Harrod ME; Franklin E; Barratt MJ; Masters J; Nguyen L; Adiraju S; Gerber C, 2022, 'Wastewater analysis for psychoactive substances at music festivals across New South Wales, Australia in 2019–2020', Clinical Toxicology, 60, pp. 440 - 445, http://dx.doi.org/10.1080/15563650.2021.1979233

Journal articles | 2022

Camacho X; Schaffer A; Buckley N; Pratt N; Brett J; Henry D; Pearson S-A, 2022, 'Trends in dispensing and utilisation of sustained-release tapentadol in Australia.', International Journal of Population Data Science, 7, http://dx.doi.org/10.23889/ijpds.v7i3.1978

Journal articles | 2022

Chiew AL; Raubenheimer JE; Berling I; Buckley NA; Becker T; Chan B; Brett J, 2022, 'Just ‘nanging’ around – harmful nitrous oxide use: a retrospective case series and review of Internet searches, social media posts and the coroner's database', Internal Medicine Journal, 52, pp. 1724 - 1732, http://dx.doi.org/10.1111/imj.15391

Journal articles | 2022

Healey A; Siefried KJ; Harrod ME; Franklin E; Peacock A; Barratt MJ; Brett J, 2022, 'Correlates of higher-risk drug-related behaviours at music festivals in New South Wales, Australia', Drug and Alcohol Review, 41, pp. 320 - 329, http://dx.doi.org/10.1111/dar.13404

Journal articles | 2022

Murnion B; Schaffer A; Cairns R; Brett J, 2022, 'Gabapentinoids: repeating mistakes of the past?', Addiction, 117, pp. 2969 - 2971, http://dx.doi.org/10.1111/add.15970

Journal articles | 2022

Page R; Healey A; Siefried KJ; Harrod ME; Franklin E; Peacock A; Barratt MJ; Brett J; Peacock A, 2022, 'Barriers to help-seeking among music festival attendees in New South Wales, Australia', Drug and Alcohol Review, 41, pp. 1322 - 1330, http://dx.doi.org/10.1111/dar.13479

Journal articles | 2022

Schaffer AL; Chia J; Brett J; Pearson S; Falster MO, 2022, 'A nationwide study of multimedicine use in people treated with cardiovascular medicines in Australia', Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy, 42, pp. 828 - 836, http://dx.doi.org/10.1002/phar.2735

Journal articles | 2022

Varney B; Zoega H; Gillies MB; Brett J; Pearson SA; Havard A, 2022, 'Prescription opioid use in Australian women of reproductive age: Implications for unplanned pregnancies', British Journal of Clinical Pharmacology, 88, pp. 1298 - 1320, http://dx.doi.org/10.1111/bcp.15074

Journal articles | 2021

Braithwaite HE; Darley DR; Brett J; Day RO; Carland JE, 2021, 'Identifying the association between tacrolimus exposure and toxicity in heart and lung transplant recipients: A systematic review', Transplantation Reviews, 35, http://dx.doi.org/10.1016/j.trre.2021.100610

Journal articles | 2021

Brett J; Pearson SA; Daniels B; Wylie CE; Buckley NA, 2021, 'A cross sectional study of psychotropic medicine use in Australia in 2018: A focus on polypharmacy', British Journal of Clinical Pharmacology, 87, pp. 1369 - 1377, http://dx.doi.org/10.1111/bcp.14527

Journal articles | 2021

Busingye D; Daniels B; Brett J; Pollack A; Belcher J; Chidwick K; Blogg S, 2021, 'Patterns of real-world opioid prescribing in Australian general practice (2013-18)', Australian Journal of Primary Health, 27, pp. 416 - 424, http://dx.doi.org/10.1071/PY20270

Journal articles | 2021

Cunio CB; Uster DW; Carland JE; Buscher H; Liu Z; Brett J; Stefani M; Jones GRD; Day RO; Wicha SG; Stocker SL, 2021, 'Towards precision dosing of vancomycin in critically ill patients: an evaluation of the predictive performance of pharmacometric models in ICU patients', Clinical Microbiology and Infection, 27, pp. 783.e7 - 783.e14, http://dx.doi.org/10.1016/j.cmi.2020.07.005

Journal articles | 2021

Schaffer AL; Busingye D; Chidwick K; Brett J; Blogg S, 2021, 'Pregabalin prescribing patterns in Australian general practice, 2012–2018: a cross-sectional study', BJGP Open, 5, pp. 1 - 10, http://dx.doi.org/10.3399/bjgpopen20X101120

Journal articles | 2021

Stocker SL; Carland JE; Reuter SE; Stacy AE; Schaffer AL; Stefani M; Lau C; Kirubakaran R; Yang JJ; Shen CFJ; Roberts DM; Marriott DJE; Day RO; Brett J, 2021, 'Evaluation of a Pilot Vancomycin Precision Dosing Advisory Service on Target Exposure Attainment Using an Interrupted Time Series Analysis', Clinical Pharmacology and Therapeutics, 109, pp. 212 - 221, http://dx.doi.org/10.1002/cpt.2113

Journal articles | 2021

Uster DW; Stocker SL; Carland JE; Brett J; Marriott DJE; Day RO; Wicha SG, 2021, 'A Model Averaging/Selection Approach Improves the Predictive Performance of Model-Informed Precision Dosing: Vancomycin as a Case Study (vol 109, pg 175, 2021)', CLINICAL PHARMACOLOGY & THERAPEUTICS, 110, pp. 1401 - 1401, http://dx.doi.org/10.1002/cpt.2353

Journal articles | 2021

Uster DW; Stocker SL; Carland JE; Brett J; Marriott DJE; Day RO; Wicha SG, 2021, 'A Model Averaging/Selection Approach Improves the Predictive Performance of Model-Informed Precision Dosing: Vancomycin as a Case Study', Clinical Pharmacology and Therapeutics, 109, pp. 175 - 183, http://dx.doi.org/10.1002/cpt.2065

Journal articles | 2020

Black E; Govindasamy L; Auld R; McArdle K; Sharpe C; Dawson A; Vazquez S; Brett J; Friend C; Shaw V; Tyner S; McDonald C; Koop D; Tall G; Welsby D; Habig K; Madeddu D; Cretikos M, 2020, 'Toxicological analysis of serious drug-related harm among electronic dance music festival attendees in New South Wales, Australia: A consecutive case series', Drug and Alcohol Dependence, 213, http://dx.doi.org/10.1016/j.drugalcdep.2020.108070

Journal articles | 2020

Brett J; Anthony C; Day R, 2020, 'Off-label quetiapine prescribing in general hospital inpatients', Journal of Pharmacy Practice and Research, http://dx.doi.org/10.1002/jppr.1608

Journal articles | 2020

Brett J; Wylie C; Brown J, 2020, 'A case of significant hypotension following a human ingestion of veterinary pimobendan', Clinical Toxicology, 58, pp. 146 - 148, http://dx.doi.org/10.1080/15563650.2019.1613550

Journal articles | 2020

Chiu T; Brett J; Pearson S; Schaffer A, 2020, 'Patterns of pregabalin initiation and discontinuation after its subsidy in Australia', British Journal of Clinical Pharmacology, 86, pp. 1882 - 1887, http://dx.doi.org/10.1111/bcp.14276

Journal articles | 2020

Coleman L; Brett J; Daniels B; Pearson S; Falster M, 2020, 'Medicine reviews: do they reduce benzodiazepine use in older Australians?', Public Health Research & Practice, 31, http://dx.doi.org/10.17061/phrp30452015

Journal articles | 2020

Gisev N; Brett J; Peacock A, 2020, 'Extra-medical use of antipsychotics: what can be learnt from experiences with other prescription medicines?', Addiction, 115, pp. 1203 - 1205, http://dx.doi.org/10.1111/add.14823

Journal articles | 2020

Stefani M; Roberts DM; Brett J, 2020, 'High-dose insulin euglycemic therapy to treat cardiomyopathy associated with massive venlafaxine overdose', Clinical Toxicology, 58, pp. 299 - 300, http://dx.doi.org/10.1080/15563650.2019.1638930

Journal articles | 2020

Wylie CE; Daniels B; Brett J; Pearson SA; Buckley NA, 2020, 'A national study on prescribed medicine use in Australia on a typical day', Pharmacoepidemiology and Drug Safety, 29, pp. 1046 - 1053, http://dx.doi.org/10.1002/pds.5093

Journal articles | 2020

Zheng D; Brett J; Daniels B; Buckley NA; Pearson SA; Schaffer AL, 2020, 'Potentially inappropriate benzodiazepine use in Australian adults: A population-based study (2014–2017)', Drug and Alcohol Review, 39, pp. 575 - 582, http://dx.doi.org/10.1111/dar.13086

Journal articles | 2019

Brett J; Wylie C; Raubenheimer J; Isbister G; Buckley N, 2019, 'The relative lethal toxicity of pharmaceutical and illicit substances; A 16-year study of the Greater Newcastle Hunter Area, Australia', British journal of clinical

Journal articles | 2019

Chalmers K; Badgery-Parker T; Pearson SA; Brett J; Scott I; Elshaug AG, 2019, 'Measuring 21 low-value health care procedures in Australian private health insurance claims data (2010 – 2014)', BMJ

Journal articles | 2019

Sandaradura I; Brett J; Milliken S, 2019, 'A study of piperacillin pharmacokinetics during febrile neutropenia', Journal of Infection and Chemotherapy

Journal articles | 2018

Badgery-Parker T; Pearson SA; Chalmers K; Brett J; Scott IA; Dunn S; Onley N; Elshaug AG, 2018, 'Low-value care in Australian public hospitals: Prevalence and trends over time', BMJ Quality and Safety, 28, pp. 205 - 214, http://dx.doi.org/10.1136/bmjqs-2018-008338

Journal articles | 2018

Brett J; Maust DT; Bouck Z; Ignacio RV; Mecredy G; Kerr EA; Bhatia S; Elshaug AG; Pearson SA, 2018, 'Benzodiazepine Use in Older Adults in the United States, Ontario, and Australia from 2010 to 2016', Journal of the American Geriatrics Society, 66, pp. 1180 - 1185, http://dx.doi.org/10.1111/jgs.15292

Journal articles | 2018

Brett J; Schaffer A; Dobbins T; Buckley NA; Pearson SA, 2018, 'The impact of permissive and restrictive pharmaceutical policies on quetiapine dispensing: Evaluating a policy pendulum using interrupted time series analysis', Pharmacoepidemiology and Drug Safety, 27, pp. 439 - 446, http://dx.doi.org/10.1002/pds.4408

Journal articles | 2018

Brett J; Zoega H; Buckley NA; Daniels BJ; Elshaug AG; Pearson SA, 2018, 'Choosing wisely? Quantifying the extent of three low value psychotropic prescribing practices in Australia', BMC Health Services Research, 18, pp. 1009, http://dx.doi.org/10.1186/s12913-018-3811-5

Journal articles | 2018

Chalmers K; Badgery-Parker T; Pearson SA; Brett J; Scott IA; Elshaug AG, 2018, 'Developing indicators for measuring low-value care: Mapping Choosing Wisely recommendations to hospital data', BMC Research Notes, 11, http://dx.doi.org/10.1186/s13104-018-3270-4

Journal articles | 2018

Karanges EA; Buckley NA; Brett J; Blanch B; Litchfield M; Degenhardt L; Pearson SA, 2018, 'Trends in opioid utilisation in Australia, 2006-2015: Insights from multiple metrics', Pharmacoepidemiology and Drug Safety, 27, pp. 504 - 512, http://dx.doi.org/10.1002/pds.4369

Journal articles | 2017

Brett J; Daniels B; Karanges EA; Buckley NA; Schneider C; Nassir A; McLachlan AJ; Pearson SA, 2017, 'Psychotropic polypharmacy in Australia, 2006 to 2015: a descriptive cohort study', British Journal of Clinical Pharmacology, 83, pp. 2581 - 2588, http://dx.doi.org/10.1111/bcp.13369

Journal articles | 2017

Brett J; Dawson A; Ivers R; Lawrence L; Barclay S; Conigrave K, 2017, 'Healing at home: Developing a model for ambulatory alcohol "detox" in an Aboriginal community controlled health service', International Journal of Indigenous Health, 12, pp. 24 - 38, http://dx.doi.org/10.18357/ijih121201716906

Journal articles | 2017

Brett J; Elshaug AG; Bhatia RS; Chalmers K; Badgery-Parker T; Pearson SA, 2017, 'A methodological protocol for selecting and quantifying low-value prescribing practices in routinely collected data: An Australian case study', Implementation Science, 12, pp. 58, http://dx.doi.org/10.1186/s13012-017-0585-9

Journal articles | 2017

Brett J; Karanges EA; Daniels B; Buckley NA; Schneider C; Nassir A; Zoega H; McLachlan AJ; Pearson SA, 2017, 'Psychotropic medication use in Australia, 2007 to 2015: Changes in annual incidence, prevalence and treatment exposure', Australian and New Zealand Journal of Psychiatry, 51, pp. 990 - 999, http://dx.doi.org/10.1177/0004867417721018

Journal articles | 2016

McNamara K, 2016, 'Benzodiazepines', AUSTRALIAN PRESCRIBER, 39, pp. 33 - 33, http://dx.doi.org/10.18773/austprescr.2016.016

Journal articles | 2015

Brett J; Murnion B, 2015, 'Management of benzodiazepine misuse and dependence', Australian Prescriber, 38, pp. 152 - 155, http://dx.doi.org/10.18773/austprescr.2015.055

Journal articles | 2015

Brett J; Murnion B, 2015, 'Pregabalin to treat ciguatera fish poisoning', Clinical Toxicology, 53, pp. 588, http://dx.doi.org/10.3109/15563650.2015.1052499

Journal articles | 2015

Brett J, 2015, 'Comments: Letters to the editor: Concerns about quetiapine', Australian Prescriber, 38, pp. 189 - 190

Journal articles | 2015

Brett J, 2015, 'Concerns about quetiapine', AUSTRALIAN PRESCRIBER, 38, pp. 189 - +

Journal articles | 2015

Brett J, 2015, 'Concerns about quetiapine', Australian Prescriber, 38, pp. 95 - 97, http://dx.doi.org/10.18773/austprescr.2015.032

Journal articles | 2015

Montebello ME; Brett B, 2015, 'Misuse and associated harms of quetiapine and other atypical antipsychotics', Current Topics in Behavioral Neurosciences, pp. 1 - 15, http://dx.doi.org/10.1007/7854_2015_424

Journal articles | 2014

Brett J; Dawson AH; Brown JA, 2014, 'Clenbuterol toxicity: A NSW Poisons Information Centre experience', Medical Journal of Australia, 200, pp. 219 - 221, http://dx.doi.org/10.5694/mja13.10982

Journal articles | 2013

Baysari M; Brett J; Lam V; Milder T; Killen L; Chau AMT; McMullan B; Harkness J; Marriot D; Day R, 2013, 'Pneumonia Severity Scores and Prescribing Antibiotics for Community-Acquired Pneumonia at an Australian Hospital', Journal of Pharmacy Practice and Research, 43, pp. 97 - 101

Journal articles | 2013

Brett J; Chong O; Graham GG; Ray J; Marriott D; Williams KM; Day RO, 2013, 'Antifungal Use and Therapeutic Monitoring of Plasma Concentrations of Itraconazole in Heart and Lung Transplantation Patients.', Therapeutic Drug Monitoring, 35, pp. 133 - 136, http://dx.doi.org/10.1097/FTD.0b013e318275fe69

Journal articles | 2013

Wong C; Kumar SS; Graham GG; Begg EJ; Chin P; Brett J; Ray J; Marriott D; Williams KM; Day RO, 2013, 'Comparing dose prediction software used to manage gentamicin dosing', Internal Medicine Journal, 43, pp. 519 - 525, http://dx.doi.org/10.1111/imj.12067

Journal articles | 2012

Baysari MT; Tang T; Brett J; Day RO, 2012, 'Implementation of revised aminoglycoside guidelines: Australian hospitals 'left in the lurch'', Journal of Pharmacy Practice and Research, 42, pp. 178 - 179

Journal articles | 2012

Brett J, 2012, 'Why have prison needle exchange programmes not yet been rolled out in the UK?', BMJ (Online), 345, http://dx.doi.org/10.1136/bmj.e6211

Journal articles | 2011

Lipworth WL; Kerridge I; Brett J; Day R, 2011, 'How clinical and research failures lead to suboptimal prescribing: the example of chronic gout.', British Medical Journal, 343, pp. d7459, http://dx.doi.org/10.1136/bmj.d7459

Journal articles | 2011

Lipworth WL; Kerridge IH; Brett J; Day RO, 2011, 'How clinical and resaerch failures lead to suboptimal prescribing: the example of chronic gout', British Medical Journal, 343, pp. 1 - 3

Journal articles | 2000

Day R, 2000, 'In Reply', The Australian Journal of Hospital Pharmacy, 30, pp. 120 - 120, http://dx.doi.org/10.1002/jppr2000303120a
Conference Abstracts | 2024

Chiew A; Chan BSH; Brett J; Jagarlamudi B, 2024, 'Nitrous oxide presentations: the growing trend of nitrous oxide cylinder usage', in Toxicology Communications, Taylor & Francis Group, Melbourne, Victoria, Vol. 8, presented at Toxicology and Poisons Network Australasia (TAPNA) 2024 Annual Scientific Meeting, Melbourne, Victoria, https://doi.org/10.1080/24734306.2024.2372936

Conference Abstracts | 2024

Chiew AL; Chan BSH; Brett J; Jagarlamudi B, 2024, 'Nitrous oxide presentations: the growing trend of nitrous oxide cylinder usage', in Clinical Toxicology, Taylor and Francis Group, Munich, Germany, Vol. 62, pp. 43 - 43, presented at 44th International Congress of the European Association of Poisons Centres and Clinical Toxicologists (EAPCCT), Munich, Germany, https://doi.org/10.1080/15563650.2024.2333651

Conference Presentations | 2024

Tran D; Varney B; Jones N; Bharat C; Brett J; Oei J; Pearson SA; Degenhardt L; Havard A, 2024, 'Trends in the use of opioid agonist treatment for opioid dependence in pregnancy', presented at 2024 NDARC Annual Research Symposium, Wesley Conference Centre, Sydney NSW, 20 September 2024, https://www.youtube.com/watch?v=Cph4ZrfKiMw&t=1850s

Conference Presentations | 2024

Varney B; Bharat C; Brett J; Degenhardt L; Jones N; Oei J; Pearson SA; Havard A; Tran DT, 2024, 'Use of opioid agonist therapy in pregnancy: Timing of initiation and treatment retention', presented at 2024 NDARC Annual Research Symposium, Wesley Conference Centre, Sydney NSW, 20 September 2024, https://www.youtube.com/watch?v=Cph4ZrfKiMw&t=2664s

Conference Abstracts | 2023

Acheson L; Gordon C; McKetin R; Brett J; Christmass M; Rodgers C; Lintzeris N; Dunlop A; Farrell M; Shoptaw S; Ezard N; Siefried K, 2023, 'OBJECTIVE AND SUBJECTIVE SLEEP DURING LISDEXAMFETAMINE TREATMENT OF ACUTE METHAMPHETAMINE WITHDRAWAL: NEW MEASUREMENT PARADIGM', in DRUG AND ALCOHOL DEPENDENCE, ELSEVIER IRELAND LTD, CO, Denver, Vol. 260, presented at 85th Annual Scientific Meeting of the College-on-Problems-of-Drug-Dependence (CPDD), CO, Denver, 17 July 2023 - 21 July 2023, http://dx.doi.org/10.1016/j.drugalcdep.2023.110067

Conference Abstracts | 2023

Acheson L; McKetin R; Ezard N; Lintzeris N; Brett J; Rodgers C; Christmass M; Gill A; Farrell M; Dunlop A; Shoptaw S; Siefried K, 2023, 'Participant experiences in a pilot study for methamphetamine withdrawal treatment: Implications for retention', in Drug and Alcohol Review, Wiley, Adelaide, Australia, Vol. 42, presented at The Australasian Professional Society on Alcohol and other Drugs Annual Scientific Conference, Adelaide, Australia, 12 November 2023 - 15 November 2023, http://dx.doi.org/10.1111/dar.13749

Conference Papers | 2023

Cairns R; Ali Z; Raubenheimer J; Noghrehchi F; Chitty K; Brown J; Dawson A; Isbister G; Chiew A; Brett J; Buckley N, 2023, 'A longitudinal data linkage of patients with acute poisoning, evnenomation and adverse drug reactions in New South Wales, Australia, 2011-2020: the PAVLOVA Cohort', in TOXICOLOGY COMMUNICATIONS, TAYLOR & FRANCIS LTD

Conference Abstracts | 2023

Moller C; Siefried K; Clifford B; Acheson L; Brett J; Dunlop A; Haber P; Christmass M; Lintzeris N; Morley K; Shoptaw S; Trivedi M; Ezard N, 2023, 'Oral naltrexone-bupropion combination pharmacotherapy for methamphetamine use disorder: Pilot study protocol', in Drug and Alcohol Review, Wiley, Adelaide, Australia, Vol. 42, presented at The Australasian Professional Society on Alcohol and other Drugs Annual Scientific Conference, Adelaide, Australia, 12 November 2023 - 15 November 2023, http://dx.doi.org/10.1111/dar.13749

Conference Papers | 2023

Piatkowski T; Wardle F; Peacock A; Hill P; Clifford S; Miller M; Dietze PM; Douglass CH; Brett J; Lim MSC; Wright CJC, 2023, 'Drug checking up north: Would festival patrons in the Northern Territory use this harm reduction service?', in DRUG AND ALCOHOL REVIEW, WILEY, pp. S143 - S144

Conference Presentations | 2022

Acheson L; Ezard N; Lintzeris N; Dunlop A; Brett J; Rodgers C; Gill A; Christmass M; McKetin R; Farrell M; Shoptaw S; Siefried K, 2022, 'Lisdexamfetamine for the treatment of acute methamphetamine withdrawal: A pilot safety and feasibility trial', presented at The 2022 APSAD Scientific Alcohol and Drugs Conference, Darwin, Australia, 09 October 2022 - 12 October 2022, https://onlinelibrary.wiley.com/doi/epdf/10.1111/dar.13537

Conference Abstracts | 2022

Acheson LS; Gordon C; Ezard N; Lintzeris N; Dunlop AJ; Brett J; Rodgers C; Gill A; Christmass M; McKetin R; Farrell M; Shoptaw S; Siefried KJ, 2022, 'An exploratory analysis of actigraphy and sleep diaries in a methamphetamine withdrawal clinical trial', in DRUG AND ALCOHOL REVIEW, WILEY, Vol. 41, pp. S23 - S24, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000862018700042&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Abstracts | 2022

Bruno C; Havard A; Gillies M; Coghill D; Brett J; Guastella A; Pearson S-A; Zoega H, 2022, 'Patterns of ADHD medicine use: A population-based study among Australian children and adults (2013-2020)', in PHARMACOEPIDEMIOLOGY AND DRUG SAFETY, WILEY, Vol. 31, pp. 71 - 71, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000859084400136&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Abstracts | 2022

Freestone J; Ezard N; Brett J; Roberts DM; Murray J; Prestage G; Hammoud M; Siefried KJ, 2022, '"Sometimes I have a duty of care not to call 000": Reported practices, attitudes and factors influencing consumer responses to GHB overdose', in DRUG AND ALCOHOL REVIEW, WILEY, Vol. 41, pp. S64 - S64, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000862018700111&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Abstracts | 2022

Knock E; Ezard N; Day R; Siefried KJ; Liknaitzky P; Ross M; Albert S; Brett J, 2022, 'A study protocol for the PsiMA trial: Psilocybin assisted psychotherapy for methamphetamine use disorder', in DRUG AND ALCOHOL REVIEW, WILEY, Vol. 41, pp. S82 - S82, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000862018700142&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Abstracts | 2022

Schaffer AL; Brett J; Buckley NA; Pearson SA, 2022, 'Trajectories of pregabalin use and their association with longitudinal changes in opioid and benzodiazepine use', in Pain, Wolters Kluwer, United States, Vol. 163, pp. E614 - E621, United States, http://dx.doi.org/10.1097/j.pain.0000000000002433

Conference Papers | 2021

Black E; Monds L; Chan B; Brett J; Acheson LS; Hutton J; Penm J; Demirkol A; Lintzeris N, 2021, 'THE ONE STUDY (OVERDOSE AND TAKE-HOME NALOXONE IN EMERGENCY SETTINGS): A PILOT STUDY EXAMINING FEASIBILITY OF DELIVERING BRIEF INTERVENTIONS ADDRESSING OVERDOSE PREVENTION WITH 'TAKE-HOME NALOXONE' SUPPLY IN EMERGENCY DEPARTMENT SETTINGS', in DRUG AND ALCOHOL REVIEW, WILEY, pp. S47 - S47, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000715073200123&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Presentations | 2021

Page RMS; Healey A; Siefried K; Harrod M; Franklin E; Barratt M; Peacock A; Brett J; Peacock A, 2021, 'Barriers to seeking help among music festival attendees in New South Wales, Australia', presented at The APSAD Scientific Drug and Alcohol Conference, Virtual, 07 November 2021 - 10 November 2021, http://dx.doi.org/10.1111/dar.13384

Conference Papers | 2021

Ryan T; Do A; Auld R; Brown JA; Jiranantakan T; Brett J; Harper CE; Irwin M, 2021, 'A HARMLESS FANTASY? INCREASING GHB-RELATED EMERGENCY DEPARTMENT PRESENTATIONS IN NEW SOUTH WALES', in DRUG AND ALCOHOL REVIEW, WILEY, pp. S32 - S33, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000715073200084&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Presentations | 2021

Siefried K; Arunogiri S; Brett J; McKetin R; Acheson LS; Knock E; Farrell M; Dunlop A; Lintzeris N; Ezard N, 2021, 'The future of pharmacotherapy clinical trials in Australia: the OLAM trial; the MOXY trial; the PSIMA trial; the TINA trial', presented at The APSAD Scientific Drug and Alcohol Conference, Virtual, 07 November 2021 - 10 November 2021, http://dx.doi.org/10.1111/dar.13384

Conference Presentations | 2021

Siefried K; McKetin R; Bedi G; Brett J; Arunogiri S; Dunlop A; Lintzeris N; Ezard N, 2021, 'Symposium: An update on pharmacotherapy trials for substance use disorder - methamphetamine type and withdrawal in Australia', presented at The APSAD Scientific Drug and Alcohol Conference, 07 November 2021 - 10 November 2021, http://dx.doi.org/10.1111/dar.13384

Conference Abstracts | 2020

Chiew AL; Becker T; Chan BS; Brett J, 2020, 'Just "nanging" around: case series of neurological sequelae from chronic nitrous oxide abuse', in CLINICAL TOXICOLOGY, TAYLOR & FRANCIS LTD, Vol. 58, pp. 568 - 568, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000531053300149&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Conference Abstracts | 2019

Daniels B; Wylie C; Pearson S-A; Brett J; Buckley N, 2019, 'A day in the life: Prescription medicine use in Australia', in PHARMACOEPIDEMIOLOGY AND DRUG SAFETY, WILEY, Vol. 28, pp. 545 - 545, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000481785604064&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Reports | 2013

Lukins TR; Pett SL; Brett J, 2013, Is it worth the weight?

NHMRC Investigator Grant: Opioid safety in pregnancy

IHIF Grant: Pharmacogenomics in mental health

IHIF Grant: Take home naloxone in Emergency Departments

Gustav Nossal Award for top ranking NH&MRC Clinical Research Postgraduate Scholarship applicant nationally – 2015.
NSW Aboriginal Health Award for integrated planning and service delivery – 2014.
Aboriginal Drug and Alcohol Network (AH&MRC) project of the year award – 2014.
Registrar of the year award: St. Vincent’s Hospital, Sydney - 2012
Final Year Medal – Goyder Scholarship for Clinical Excellence in Medicine and Surgery- 2005

Pharmacoepidemiology: Opioid and psychotropics quality and safety of prescribing and safety in pregnancy (NHMRC Investiagtor Grant)

Psychedelic-assisted psychotherapy and micro-dosing: Methamphetamine use disorder, depression (Black Dog and NCCRED Grants)

Drugs of abuse, drug overdose response and prevention

Toxicoepidemiology: The relative toxicity of drugs taken in overdose

Pharmacogenomics: The role of pharmacogenomics in mental health

Therapeutic Drug Monitoring: The implementation of a TDM service at St. Vincent's Hospital, antimicrobial TDM, tacrolimus toxicity in transplant medicine.

My Research Supervision

Honors/ILP x 10

PhD x2

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Dr Jonathan Brett