Professor Fabio Luciani

Professor Fabio Luciani

Professor

INSTITUTION AND LOCATION

DEGREE

 

 

Completion Date

 

FIELD OF STUDY

 

University of Bologna, Italy

 

Humboldt University, Berlin, Germany

 

University of New South Wales, Australia

 

University of New South Wales, Australia

Masters

 

Ph.D.

 

Post-doctoral

 

Research Fellow

06/2000

 

06/2006

 

06/2008

 

06/2009

Physics

 

Theoretical Biology

Biophysics

Theoretical Biology

 

Bioinformatics Immunology

Medicine & Health
School of Biomedical Sciences

I am a Professor in Systems Immunology and Machine Learning at the School of Medical Sciences at UNSW Sydney, and I am a visiting fellow at the Garvan Institute for Medical Research and at the Weill Cornell College of Medicine NY, USA.

My research program uses a Systems Immunology approach to study of T cell responses with the ultimate goal to develop and new immunotherapies that can be used against incurable cancer and autoimmune diseases. I am passionate about Immunology, and of discov...

Phone
+61 (2) 9385 3838
E-mail
luciani@unsw.edu.au
Location
Lowy Buidling

I have received fundings from ARC, NHMCR, JDRF and NIH

Private funding from industry involved in technology development and single cell genomics.

As a theoretical physicist by training, I utilise an interdisciplinary approach to understand these responses. In particular, I am a Systems Immunologist.  Systems immunology is an interdisciplinary field that applies systems biology and computational modeling approaches to study the immune system as a complex and integrated system. It aims to understand the dynamic interactions and behaviors of various components of the immune system, such as immune cells, proteins, and signaling pathways, in response to infections, diseases, and other biological challenges.

Key aspects and goals of my systems immunology research include 

  1. Personalized Medicine In CAR T cell therapies: We utilise single cell multi omics to development a personalized approach to CAR T cell therapies, and dissect the individual variation of the immune responses that can be used to improve treatment and hence precision medicine. 

  2. Artificial intelligence and computational Analysis of immune receptors: we are working on develping targeted precise therapies against autoimmune diseases using structural predictions and single cell multi omics. 

  3. Coeliac Disease  We aim to gain insights into the immune responses associated with coeliac diseases, and specifically in those immune cells that acquire somatic mutations and go rogue, breaking the natural immunological tolerance.

  4. Integration of Data: integrate large datasets from various sources, including genomics, transcriptomics, proteomics, and immunophenotyping, to gain a comprehensive view of immune system function.

 

My Research Supervision

3 PhD students, 2 honours, and 2 postdocs.