Professor Elgene Lim

Professor Elgene Lim

Professor

03/10

Post Doctorate

Cancer Biology

Dana-Farber Cancer Institute (DFCI), Harvard Medical School, Boston, USA

02/10

PhD

Molecular Biology

Walter & Eliza Hall Institute of Medical Research (WEHI), Melbourne University, Australia

12/06

FRACP

Internal Medicine & Medical Oncology

Royal Australasian College of Physicians (RACP), Australia

12/95

MBBS

Medicine & Surgery

Melbourne University, Victoria, Australia

Medicine & Health
School of Clinical Medicine

Elgene was awarded his medical degree from the University of Melbourne. He obtained his medical oncology fellowship from the Royal Australasian College of Physicians in 2006, and subsequently embarked on a PhD as a National Breast Cancer Foundation Scholar at the Walter & Eliza Hall Institute with eminent Australian breast cancer researchers Professors Jane Visvader & Geoffrey Lindemann. His research identified the aberrant cells in carriers of the BRCA1 mutant gene, a hereditary breast can...

Phone
02 9355 5823
E-mail
e.lim@garvan.org.au
Location
The Kinghorn Cancer Centre 370 Victoria Street Darlinghurst NSW 2010

2017-27

NBCF Endowed Chair (Co funded by Garvan Institute) ($5,000,000). Role CIA

 

2019-21

Therapeutic targeting of dual CDK4/6 inhibitor and endocrine resistant breast cancer. APP IIRS-19-054. NBCF (CIA Caldon). ($582,432) Role: CIB

 

2018-21

Transforming endocrine therapy for breast and prostate cancer. MNBCF Collaborative Research Initiative (CIA Tilley) ($2,500,000). Role: CID

 

2018-21

Pushing AR toward better outcomes in breast and prostate cancers. APP 1145777. NHMRC Project Grant (CIA Tilley) (A$1,000,000). Role: CIE

 

2018-21

Reactivating p53 to combat CDK4/6 inhibitor resistance in ER positive Breast Cancer. St Vincent’s Clinic Foundation ($40,000) Role: CIA.

 

2019-20

Targeting the p53 pathway in the age of CDK4/6 inhibitor resistant ER+ breast cancer. APP IIRS-19-053. NBCF (CIA Portman). ($197,825). Role: CIB.

 

2017-20

Targeting the Oncoprotein MDMX as a Novel Treatment for Triple Negative Breast Cancer. APP 1123057. NHMRC Project Grant (CIA Haupt) (A$800,000). Role: CIC

 

2017-20

Four dimensional epigenome remodelling: implications for endocrine resistance in breast cancer. APP 1128916.  NHMRC Project Grant (CIA Clark) (A$828,559.50). Role: CIC

 

2017-20

The clinical significance of sex hormone crosstalk in ER+ breast cancer. APP 1130077. NHMRC Project Grant (CIA Tilley) (A$1,009,006). Role: CIC

 

2017-9

Evaluating ODM201, an AR degrader, in breast cancer. Bayer Pharm (A$200,000). Role CIA.

 

2017-9

Progesterone as an anticancer therapy in early breast cancer. RG 17-08. Cancer Council of New South Wales Project Grant (A$450,000). Role: CIA

 

Past

 

 

2017-8

2016-8

Metabolic effects of exercise on breast cancer. Thelma Greig Cancer Grant. St Vincent’s Clinic Foundation (A$50,000). Role: CIA.

A novel approach to overcome therapy-resistance in breast cancer. APP 1107170. Cancer Australia. (A$600,000). Role: CIA.

 

2016-7

Identification of breast cancer subtype-specific tumour antigens using the local immune response. NBCF (A$200,000). Role: CIA.

 

2016-7

Evaluating MDM2 inhibitors in breast cancer. Novartis Australia (A$51,000). Role: CIA.

 

2014-7

Sensitizing breast cancers to hormone receptor-directed therapies. NBCF & Victorian Cancer Agency Practitioner Fellowship (A$800,000). Role: CIA

 

2015-6

Targeting the p53 pathway in ER-positive breast cancer. Australia New Zealand Breast Cancer Trialist Group (A$91,600). Role: CIA.

 

2014-5

Evaluation of concurrent chemoendocrine therapy and predictive biomarkers for HR+ breast cancer. Ramaciotti Award, Perpetual Trustees Australia (A$75,000). Role: CIA.

 

2013-4

Exploiting DNA repair deficits in non BRCA mutation associated breast cancer. Cancer Research Grant, Pfizer Australia (A$50,000). Role: CIA.

 

2011-4

The identification of novel treatments for poor prognosis subgroups of breast cancer. NHMRC Overseas Postdoctoral Fellowship (A$360,000). Role: CIA.

 

2010

Fulbright Victoria Fellowship. (A$25,000). Role: CIA.

2006-9

White/Zaal PhD scholarship. NBCF (A$105,000). Role: CIA.

2008

Characterization of human mammary stem and progenitor cells. Postgraduate Research award, GlaxoSmithKline Australia (A$25,000) Role: CIA.

2007

Characterization of human mammary stem and progenitor cells. Career development award, Clinical Oncological Society of Australia (A$50,000) Role: CIA.

2017

NBCF Endowed Chair

National Breast Cancer Foundation

Breast Cancer Research

2015

Connie Johnson Award

Garvan Institute

Breast Cancer Research

2014

Ramaciotti Award

Perpetual Trustees

Translational Research

2014

NBCF Practitioner Fellowship

NBCF/ Victorian Cancer Agency

Translational Research

2013

Claudia Adams Barr Fellowship

Claudia Adams Barr Foundation

Post doctoral research

2012

AACR Scholar-In-Training Award

Susan G. Komen for the Cure®

SABCS Poster ppt

2011

Overseas Postdoctoral Fellowship

NHMRC

Post doctoral research

2010

Fulbright Victoria Scholarship

US Department of State

Post doctoral research

2009

JJ Billings Overseas Fellowship

RACP

Post doctoral research

2009

Edith Moffatt Travel Award

WEHI

 

2009

Best PhD Seminar 2009

WEHI

 

2008

Best Oral Presentation

COSA ASM

Breast stem cells

2008

Early Career Bench & Bedside Collaboration Award

Victorian Cancer Agency

Breast cancer xenografts

2008

Best Oral Presentation

Melbourne Research Week

Breast stem cells

2008

Post Graduate Research Award

GlaxoSmithKline Australia

PhD in breast stem cells

2007

Post Graduate Research Award

Australian Stem Cell Centre

Post Graduate Research

PhD in breast stem cells

2007

Director’s Art in Science Prize

WEHI

 

2007

Tumour Targeting Fellowship

COSA

PhD in breast stem cells

2006

White/Zaal Scholarship

NBCF, Australia

PhD in breast stem cells

  • 2017

    2015

    NBCF Endowed Chair

    Connie Johnson Award

    National Breast Cancer Foundation

    Garvan Institute

    Breast Cancer Research

    Breast Cancer Research

  • 2017

    2014

    NBCF Endowed Chair

    Ramaciotti Award

    National Breast Cancer Foundation

    Perpetual Trustees

    Breast Cancer Research

    Translational Research

  • 2017

    2014

    NBCF Endowed Chair

    NBCF Practitioner Fellowship

    National Breast Cancer Foundation

    NBCF/ Victorian Cancer Agency

    Breast Cancer Research

    Translational Research

  • 2017

    2013

    NBCF Endowed Chair

    Claudia Adams Barr Fellowship

    National Breast Cancer Foundation

    Claudia Adams Barr Foundation

    Breast Cancer Research

    Post doctoral research

  • 2017

    2012

    NBCF Endowed Chair

    AACR Scholar-In-Training Award

    National Breast Cancer Foundation

    Susan G. Komen for the Cure®

    Breast Cancer Research

    SABCS Poster ppt

  • 2017

    2011

    NBCF Endowed Chair

    Overseas Postdoctoral Fellowship

    National Breast Cancer Foundation

    NHMRC

    Breast Cancer Research

    Post doctoral research

  • 2017

    2010

    NBCF Endowed Chair

    Fulbright Victoria Scholarship

    National Breast Cancer Foundation

    US Department of State

    Breast Cancer Research

    Post doctoral research

  • 2017

    2009

    NBCF Endowed Chair

    JJ Billings Overseas Fellowship

    National Breast Cancer Foundation

    RACP

    Breast Cancer Research

    Post doctoral research

  • 2017

    2009

    NBCF Endowed Chair

    Edith Moffatt Travel Award

    National Breast Cancer Foundation

    WEHI

    Breast Cancer Research

     

  • 2017

    2009

    NBCF Endowed Chair

    Best PhD Seminar 2009

    National Breast Cancer Foundation

    WEHI

    Breast Cancer Research

     

  • 2017

    2008

    NBCF Endowed Chair

    Best Oral Presentation

    National Breast Cancer Foundation

    COSA ASM

    Breast Cancer Research

    Breast stem cells

  • 2017

    2008

    NBCF Endowed Chair

    Early Career Bench & Bedside Collaboration Award

    National Breast Cancer Foundation

    Victorian Cancer Agency

    Breast Cancer Research

    Breast cancer xenografts

  • 2017

    2008

    NBCF Endowed Chair

    Best Oral Presentation

    National Breast Cancer Foundation

    Melbourne Research Week

    Breast Cancer Research

    Breast stem cells

  • 2017

    2008

    NBCF Endowed Chair

    Post Graduate Research Award

    National Breast Cancer Foundation

    GlaxoSmithKline Australia

    Breast Cancer Research

    PhD in breast stem cells

  • 2017

    2007

    NBCF Endowed Chair

    Post Graduate Research Award

    National Breast Cancer Foundation

    Australian Stem Cell Centre

    Post Graduate Research

    Breast Cancer Research

    PhD in breast stem cells

  • 2017

    2007

    NBCF Endowed Chair

    Director’s Art in Science Prize

    National Breast Cancer Foundation

    WEHI

    Breast Cancer Research

     

  • 2017

    2007

    NBCF Endowed Chair

    Tumour Targeting Fellowship

    National Breast Cancer Foundation

    COSA

    Breast Cancer Research

    PhD in breast stem cells

  • 2017

    2006

    NBCF Endowed Chair

    White/Zaal Scholarship

    National Breast Cancer Foundation

    NBCF, Australia

    Breast Cancer Research

    PhD in breast stem cells

My Research Supervision

  1. Allegra Freelander PhD student. Targeting the Androgen Receptor in endocrine-resistant breast cancer.
  2. Dr Sara Wahlroos. PhD student. Defining the role of exercise and systemic therapies in breast cancer.
  3. Sarah Alexandrou. PhD student. Overcoming resistance to CDK4/6 inhibitors in breast cancer.
  4. Dr Julia Chen. PhD Student. Novel therapeutic targeting stromal and epithelial interactions in triple negative breast cancer (TNBC) 
  5. Dr Katherine Manakas. PhD Student. MDM2 inhibitors for the treatment of advanced hormone receptor positive Breast Cancer

My Teaching

We supervise PhD, honours and medical students in our laboratory.

I also teach Medical Students and Physician Trainees at St Vincent's Hospital.

Completed PhD students: Dr Kee Ming Chia (2019)

Current PhD students: Allegra Freelander, Sarah Alexandrou, Dr Sarah Wahlroos

Current Oncology Fellow: Dr Julia Chen

Past Medical Students: James Williams (UNDA 2017-8), Christopher Hudson (UNDA 2018)

Past Oncology Fellows: Dr Emma Carson