Dr Bethany Horsburgh

Research Associate

BSc (Adv) (Hons), PhD (Medicine)

Medicine & Health

The Kirby Institute

Bethany is a Research Associate, working with Dr Francesca di Giallonardo and A/Prof Rowena Bull to develop and validate whole-genome sequencing methodologies for HIV and Hepatitis C as part of the H2Seq MRFF grant.

Bethany completed her Bachelor of Science (Advanced) with Honours in 2016 at the University of Sydney, majoring in Immunobiology and Biology. She then completed her PhD in 2020 at the Westmead Institute for Medical Research. Her studies focused on the use of single-copy assays and high-throughput sequencing to characterise full-length HIV genomes during suppressive antiretroviral therapy.

Post-PhD she worked as a research assistant, continuing to develop and utilise high-throughput sequencing to understand viral genomes. In 2021 her work assisted in the identification of a previously uncharacterised strain of Hendra virus.

Phone

+61 2 9348 0888

E-mail

bhorsburgh@kirby.unsw.edu.au

Location

Level 5 Wallace Wurth Building

Book Chapters | 2018

Horsburgh BA; Palmer S, 2018, 'Measuring HIV persistence on antiretroviral therapy', in Advances in Experimental Medicine and Biology, pp. 265 - 284, http://dx.doi.org/10.1007/978-981-13-0484-2_11
Journal articles | 2024

Horsburgh BA; Walker GJ; Kelleher A; Lloyd AR; Bull RA; Giallonardo FD, 2024, 'Next-Generation Sequencing Methods for Near-Real-Time Molecular Epidemiology of HIV and HCV', Reviews in Medical Virology, 34, http://dx.doi.org/10.1002/rmv.70001

Journal articles | 2023

Speck P; MacKenzie J; Bull RA; Slobedman B; Drummer H; Fraser J; Herrero L; Helbig K; Londrigan S; Moseley G; Prow N; Hansman G; Edwards R; Ahlenstiel C; Abendroth A; Tscharke D; Hobson-Peter J; Kriiger-Loteri R; Parry R; Marsh G; Harding E; Jacques DA; Gartner MJ; Lee WS; McAuley J; Vaz P; Sainsbury F; Tate MD; Sinclair J; Imrie A; Rawlinson S; Harman A; Carr JM; Monson EA; Hibma M; Mahony TJ; Tu T; Center RJ; Shrestha LB; Hall R; Warner M; Ward V; Anderson DE; Eyre NS; Netzler NE; Peel AJ; Revill P; Beard M; Legione AR; Spencer AJ; Idris A; Forwood J; Sarker S; Purcell DFJ; Bartlett N; Deerain JM; Brew BJ; Asgari S; Farrell H; Khromykh A; Tuipulotu DE; Anderson D; Mese S; Tayyar Y; Edenborough K; Uddin JM; Hussain A; Daymond CJI; Agius J; Johnson KN; Shirmast P; Abedinzadeshahri M; MacDiarmid R; Ashley CL; Laws J; Furfaro LL; Burton TD; Johnson SMR; Telikani Z; Petrone M; Roby JA; Samer C; Suhrbier A; Van Der Kamp A; Cunningham A; Donato C; Mahar J; Black WD; Vasudevan S; Lenchine R; Spann K; Rawle DJ; Rudd P; Neil J; Kingston R; Newsome TP; Kim KW; Mak J; Lowry K; Bryant N, 2023, 'Statement in Support of: "Virology under the Microscope - a Call for Rational Discourse"', mSphere, 8, http://dx.doi.org/10.1128/msphere.00165-23

Journal articles | 2023

Speck P; Mackenzie J; Bull RA; Slobedman B; Drummer H; Fraser J; Herrero L; Helbig K; Londrigan S; Moseley G; Prow N; Hansman G; Edwards R; Ahlenstiel C; Abendroth A; Tscharke D; Hobson-Peters J; Kriiger-Loterio R; Parry R; Marsh G; Harding E; Jacques DA; Gartner MJ; Lee WS; McAuley J; Vaz P; Sainsbury F; Tate MD; Sinclair J; Imrie A; Rawlinson S; Harman A; Carr JM; Monson EA; Hibma M; Mahony TJ; Tu T; Center RJ; Shrestha LB; Hall R; Warner M; Ward V; Anderson DE; Eyre NS; Netzler NE; Peel AJ; Revill P; Beard M; Legione AR; Spencer AJ; Idris A; Forwood J; Sarker S; Purcell DFJ; Bartlett N; Deerain JM; Brew BJ; Asgari S; Farrell H; Khromykh A; Tuipulotu DE; Anderson D; Mese S; Tayyar Y; Edenborough K; Uddin JM; Hussain A; Daymond CJI; Agius J; Johnson KN; Shirmast P; Abedinzadeshahri M; MacDiarmid R; Ashley CL; Laws J; Furfaro LL; Burton TD; Johnson SMR; Telikani Z; Petrone M; Roby JA; Samer C; Suhrbier A; Van Der Kamp A; Cunningham A; Donato C; Mahar J; Black WD; Vasudevan S; Lenchine R; Spann K; Rawle DJ; Rudd P; Neil J; Kingston R; Newsome TP; Kim KW; Mak J; Lowry K; Bryant N, 2023, 'Statement in Support of: “Virology under the Microscope-a Call for Rational Discourse”', Journal of Virology, 97, http://dx.doi.org/10.1128/jvi.00451-23

Journal articles | 2023

Speck P; Mackenzie J; Bull RA; Slobedman B; Drummer H; Fraser J; Herrero L; Helbig K; Londrigan S; Moseley G; Prow N; Hansman G; Edwards R; Ahlenstiel C; Abendroth A; Tscharke D; Hobson-Peters J; Kriiger-Loterio R; Parry R; Marsh G; Harding E; Jacques DA; Gartner MJ; Lee WS; McAuley J; Vaz P; Sainsbury F; Tate MD; Sinclair J; Imrie A; Rawlinson S; Harman A; Carr JM; Monson EA; Hibma M; Mahony TJ; Tu T; Center RJ; Shrestha LB; Hall R; Warner M; Ward V; Anderson DE; Eyre NS; Netzler NE; Peel AJ; Revill P; Beard M; Legione AR; Spencer AJ; Idris A; Forwood J; Sarker S; Purcell DFJ; Bartlett N; Deerain JM; Brew BJ; Asgari S; Farrell H; Khromykh A; Tuipulotu DE; Anderson D; Mese S; Tayyar Y; Edenborough K; Uddin JM; Hussain A; Daymond CJI; Agius J; Johnson KN; Shirmast P; Abedinzadeshahri M; MacDiarmid R; Ashley CL; Laws J; Furfaro LL; Burton TD; Johnson SMR; Telikani Z; Petrone M; Roby JA; Samer C; Suhrbier A; Van Der Kamp A; Cunningham A; Donato C; Mahar J; Black WD; Vasudevan S; Lenchine R; Spann K; Rawle DJ; Rudd P; Neil J; Kingston R; Newsome TP; Kim KW; Mak J; Lowry K; Bryant N, 2023, 'Statement in Support of: “Virology under the Microscope—a Call for Rational Discourse”', mBio, 14, http://dx.doi.org/10.1128/mbio.00815-23

Journal articles | 2022

Annand EJ; Horsburgh BA; Xu K; Reid PA; Poole B; de Kantzow MC; Brown N; Tweedie A; Michie M; Grewar JD; Jackson AE; Singanallur NB; Plain KM; Kim K; Tachedjian M; van der Heide B; Crameri S; Williams DT; Secombe C; Laing ED; Sterling S; Yan L; Jackson L; Jones C; Plowright RK; Peel AJ; Breed AC; Diallo I; Dhand NK; Britton PN; Broder CC; Smith I; Eden JS, 2022, 'Novel Hendra Virus Variant Detected by Sentinel Surveillance of Horses in Australia', Emerging Infectious Diseases, 28, pp. 693 - 704, http://dx.doi.org/10.3201/eid2803.211245

Journal articles | 2022

Duette G; Hiener B; Morgan H; Mazur FG; Mathivanan V; Horsburgh BA; Fisher K; Tong O; Lee E; Ahn H; Shaik A; Fromentin R; Hoh R; Bacchus-Souffan C; Nasr N; Cunningham AL; Hunt PW; Chomont N; Turville SG; Deeks SG; Kelleher AD; Schlub TE; Palmer S, 2022, 'The HIV-1 proviral landscape reveals that Nef contributes to HIV-1 persistence in effector memory CD4⁺ T cells', Journal of Clinical Investigation, 132, http://dx.doi.org/10.1172/JCI154422

Journal articles | 2022

Eden JS; Sikazwe C; Xie R; Deng YM; Sullivan SG; Michie A; Levy A; Cutmore E; Blyth CC; Britton PN; Crawford N; Dong X; Dwyer DE; Edwards KM; Horsburgh BA; Foley D; Kennedy K; Minney-Smith C; Speers D; Tulloch RL; Holmes EC; Dhanasekaran V; Smith DW; Kok J; Barr IG; Alafaci A; Carter I; Daley A; Francis M; Kesson A; Moore H; Ngo C; Tran T, 2022, 'Off-season RSV epidemics in Australia after easing of COVID-19 restrictions', Nature Communications, 13, http://dx.doi.org/10.1038/s41467-022-30485-3

Journal articles | 2022

Horsburgh BA; Hiener B; Fisher K; Lee E; Morgan H; Eden JS; Von Stockenstrom S; Odevall L; Milush JM; Hoh R; Fromentin R; Chomont N; Hecht FM; Schlub TE; Deeks SG; Palmer S, 2022, 'Cellular Activation, Differentiation, and Proliferation Influence the Dynamics of Genetically Intact Proviruses over Time', Journal of Infectious Diseases, 225, pp. 1168 - 1178, http://dx.doi.org/10.1093/infdis/jiab291

Journal articles | 2022

Taylor J; Thompson K; Annand EJ; Massey PD; Bennett J; Eden JS; Horsburgh BA; Hodgson E; Wood K; Kerr J; Kirkland P; Finlaison D; Peel AJ; Eby P; Durrheim DN, 2022, 'Novel variant Hendra virus genotype 2 infection in a horse in the greater Newcastle region, New South Wales, Australia', One Health, 15, http://dx.doi.org/10.1016/j.onehlt.2022.100423

Journal articles | 2022

Wang Z; Dang HV; Amaya M; Xu Y; Yin R; Yan L; Hickey AC; Annand EJ; Horsburgh BA; Reid PA; Smith I; Eden JS; Xu K; Broder CC; Veesler D, 2022, 'Potent monoclonal antibody–mediated neutralization of a divergent Hendra virus variant', Proceedings of the National Academy of Sciences of the United States of America, 119, http://dx.doi.org/10.1073/pnas.2122769119

Journal articles | 2021

Morcilla V; Bacchus-Souffan C; Fisher K; Horsburgh BA; Hiener B; Wang XQ; Schlub TE; Fitch M; Hoh R; Hecht FM; Martin JN; Deeks SG; Hellerstein MK; McCune JM; Hunt PW; Palmer S, 2021, 'HIV-1 Genomes Are Enriched in Memory CD4⁺ T-Cells with Short Half-Lives', mBio, 12, http://dx.doi.org/10.1128/mBio.02447-21

Journal articles | 2021

Robertson M; Eden JS; Levy A; Carter I; Tulloch RL; Cutmore EJ; Horsburgh BA; Sikazwe CT; Dwyer DE; Smith DW; Kok J, 2021, 'The spatial-temporal dynamics of respiratory syncytial virus infections across the east–west coasts of Australia during 2016–17', Virus Evolution, 7, http://dx.doi.org/10.1093/ve/veab068

Journal articles | 2020

Horsburgh BA; Lee E; Hiener B; Eden JS; Schlub TE; Von Stockenstrom S; Odevall L; Milush JM; Liegler T; Sinclair E; Hoh R; Boritz EA; Douek DC; Fromentin R; Chomont N; Deeks SG; Hecht FM; Palmer S, 2020, 'High levels of genetically intact HIV in HLA-DR+ memory T cells indicates their value for reservoir studies', AIDS, 34, pp. 659 - 668, http://dx.doi.org/10.1097/QAD.0000000000002465

Journal articles | 2019

Horsburgh BA; Palmer S, 2019, 'For Viral Reservoir Studies, Timing Matters', Trends in Microbiology, 27, pp. 809 - 810, http://dx.doi.org/10.1016/j.tim.2019.08.003

Journal articles | 2018

Hiener B; Eden JS; Horsburgh BA; Palmer S, 2018, 'Amplification of near full-length HIV-1 proviruses for next-generation sequencing', Journal of Visualized Experiments, 2018, http://dx.doi.org/10.3791/58016

Journal articles | 2017

Hiener B; Horsburgh BA; Eden JS; Barton K; Schlub TE; Lee E; von Stockenstrom S; Odevall L; Milush JM; Liegler T; Sinclair E; Hoh R; Boritz EA; Douek D; Fromentin R; Chomont N; Deeks SG; Hecht FM; Palmer S, 2017, 'Identification of Genetically Intact HIV-1 Proviruses in Specific CD4⁺ T Cells from Effectively Treated Participants', Cell Reports, 21, pp. 813 - 822, http://dx.doi.org/10.1016/j.celrep.2017.09.081

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Dr Bethany Horsburgh