Back to
Dr Alex Hui

Dr Alex Hui

Adjunct Associate Professor
  • GradCertOcTher - School of Optometry and Vision Science, UNSW Sydney, Sydney, NSW, Australia. 2018
  • PhD in Vision Science - Centre for Contact Lens Research, School of Optometry & Vision Science, University of Waterloo, Waterloo, Ontario, Canada. 2014
  • OD - School of Optometry & Vision Science, University of Waterloo, Waterloo, Ontario, Canada. 2010
Medicine & Health
School of Optometry and Vision Science


My work centers around the development and testing of novel ways of treating ocular diseases. I have focused on utilizing contact lenses as a means to deliver pharmaceuticals to the eye, including delivery of antibiotics, anti-allergy and anti-inflammatory agents. I am interested in the development of other types of drug delivery systems for the treatment of infectious, inflammatory and allergic diseases of the eye, including development of novel eye drops and new biomaterials.

Professional Memberships

  • Fellow, American Academy of Optometry (FAAO)
  • Ezell Club, American Optometric Foundation (AOF)
  • Canadian Association of Optometrists
  • Ontario Association of Optometrists
  • College of Optometrists of Ontario

Research Groups

Research Topics

  • Dry eye: contact lens wear, innervation and symptoms, sex hormones
  • Myopia control incl. orthokeratology
  • Ocular therapeutics and drug delivery
Phone
+61 2 9385 9228
E-mail
alex.hui@unsw.edu.au
  • Book Chapters | 2024
    Shokrollahi P; Hui A, 2024, 'Advances in Contact Lenses for Ophthalmic Drug Delivery', in Current Practices in Ophthalmology, Springer Nature Singapore, pp. 99 - 113, http://dx.doi.org/10.1007/978-981-97-8140-9_8
    Book Chapters | 2019
    Hui A; Carnt N; Jalbert I, 2019, '17 Management of Contact Lens–Induced Pathology', in Contact Lenses, Elsevier, pp. 344 - 355, http://dx.doi.org/10.1016/b978-0-7020-7168-3.00017-9
    Book Chapters | 2019
    Hui A; Carnt N; Jalbert I, 2019, 'Management of Contact Lens-Induced Pathology', in Phillips A; Speedwell L (ed.), Contact Lenses, Elsevier, pp. 344 - 355
  • Journal articles | 2025
    Sara M; Chakraborty S; Chen R; Palms D; Katsifis G; Li Z; Farajikhah S; Massedupally V; Hui A; Wong EHH; Kumar N; Vasilev K; Mackenzie D; Losurdo L; Dehghani F; Jenssen H; Sorensen K; Lin JS; Barron AE; Willcox M, 2025, 'The effect of immobilisation strategies on the ability of peptoids to reduce the adhesion of P. aeruginosa strains to contact lenses', Experimental Eye Research, 250, http://dx.doi.org/10.1016/j.exer.2024.110149
    Journal articles | 2025
    Shokrollahi P; Garg P; Wulff D; Hui A; Phan CM; Jones L, 2025, 'Vat photopolymerization 3D printing optimization: Analysis of print conditions and print quality for complex geometries and ocular applications', International Journal of Pharmaceutics, 668, http://dx.doi.org/10.1016/j.ijpharm.2024.124999
    Journal articles | 2024
    Abdullah Aziz M; Kuppusamy R; Mazumder K; Hui A; Maulvi F; Stapleton F; Willcox M, 2024, 'Absorption and attachment of atropine to etafilcon A contact lenses', Contact Lens and Anterior Eye, 47, http://dx.doi.org/10.1016/j.clae.2024.102246
    Journal articles | 2024
    Dang RM; Ehrmann K; Jalbert I; Hui A; Kang P, 2024, 'Refractive power profiles of commercially available soft multifocal contact lenses for myopia control', Ophthalmic and Physiological Optics, 44, pp. 1202 - 1214, http://dx.doi.org/10.1111/opo.13345
    Journal articles | 2024
    Mishra SK; Baidya S; Bhattarai A; Shrestha S; Homagain S; Rayamajhee B; Hui A; Willcox M, 2024, 'Bacteriology of endotracheal tube biofilms and antibiotic resistance: a systematic review', Journal of Hospital Infection, 147, pp. 146 - 157, http://dx.doi.org/10.1016/j.jhin.2024.03.004
    Journal articles | 2024
    Phan CM; WY Chan V; Drolle E; Hui A; Ngo W; Bose S; Shows A; Liang S; Sharma V; Subbaraman L; Zheng Y; Shi X; Wu J; Jones L, 2024, 'Evaluating the in vitro wettability and coefficient of friction of a novel and contemporary reusable silicone hydrogel contact lens materials using an in vitro blink model', Contact Lens and Anterior Eye, 47, http://dx.doi.org/10.1016/j.clae.2024.102129
    Journal articles | 2024
    Qiu SX; Fadel D; Hui A, 2024, 'Scleral Lenses for Managing Dry Eye Disease in the Absence of Corneal Irregularities: What Is the Current Evidence?', Journal of Clinical Medicine, 13, http://dx.doi.org/10.3390/jcm13133838
    Journal articles | 2024
    Sara M; Hui A; Yasir M; Peguda HK; Kalaiselvan P; Willcox M, 2024, 'Intrastromal Corneal Ring Implants Associated Bacterial Infections', Current Eye Research, 49, pp. 1012 - 1020, http://dx.doi.org/10.1080/02713683.2024.2354438
    Journal articles | 2024
    Sara M; Yasir M; Kalaiselvan P; Hui A; Kuppusamy R; Kumar N; Chakraborty S; Yu TT; Wong EHH; Molchanova N; Jenssen H; Lin JS; Barron AE; Willcox M, 2024, 'The activity of antimicrobial peptoids against multidrug-resistant ocular pathogens', Contact Lens and Anterior Eye, 47, http://dx.doi.org/10.1016/j.clae.2024.102124
    Journal articles | 2024
    Wong KY; Phan CM; Chan YT; Yuen ACY; Zhang H; Zhao D; Chan KY; Do CW; Lam TC; Qiao JH; Wulff D; Hui A; Jones L; Wong MS, 2024, 'A review of using Traditional Chinese Medicine in the management of glaucoma and cataract', Clinical and Experimental Optometry, 107, pp. 156 - 170, http://dx.doi.org/10.1080/08164622.2023.2246480
    Journal articles | 2024
    Yamasaki K; Dantam J; Sasanuma K; Hisamura R; Mizuno Y; Hui A; Jones L, 2024, 'Impact of in vitro lens deposition and removal on bacterial adhesion to orthokeratology contact lenses', Contact Lens and Anterior Eye, 47, http://dx.doi.org/10.1016/j.clae.2023.102104
    Journal articles | 2023
    Hui A, 2023, 'Antibiotic releasing contact lenses: the future of treatment for corneal infection and injury?', Expert Review of Ophthalmology, 18, pp. 271 - 273, http://dx.doi.org/10.1080/17469899.2023.2262766
    Journal articles | 2022
    Williams R; Hui A, 2022, 'Common systemic medications that every optometrist should know', Clinical and Experimental Optometry, 105, pp. 149 - 156, http://dx.doi.org/10.1080/08164622.2021.1945409
    Journal articles | 2021
    Dang RMT; Watt K; Hui A, 2021, 'Povidone iodine for the treatment of adenoviral conjunctivitis', Clinical and Experimental Optometry, 104, pp. 308 - 314, http://dx.doi.org/10.1080/08164622.2021.1877532
    Journal articles | 2021
    Ho L; Jalbert I; Watt K; Hui A, 2021, 'Current understanding and therapeutic management of contact lens associated sterile corneal infiltrates and microbial keratitis', Clinical and Experimental Optometry, 104, pp. 323 - 333, http://dx.doi.org/10.1080/08164622.2021.1877530
    Journal articles | 2021
    Hui A; Jalbert I, 2021, 'Ocular therapeutics: from special interest to standard care', Clinical and Experimental Optometry, 104, pp. 265 - 266, http://dx.doi.org/10.1080/08164622.2021.1877535
    Journal articles | 2021
    Jones L; Hui A; Phan CM; Read ML; Azar D; Buch J; Ciolino JB; Naroo SA; Pall B; Romond K; Sankaridurg P; Schnider CM; Terry L; Willcox M, 2021, 'CLEAR - Contact lens technologies of the future', Contact Lens and Anterior Eye, 44, pp. 398 - 430, http://dx.doi.org/10.1016/j.clae.2021.02.007
    Journal articles | 2019
    Markoulli M; Hui A, 2019, 'Emerging targets of inflammation and tear secretion in dry eye disease', Drug Discovery Today, 24, pp. 1427 - 1432, http://dx.doi.org/10.1016/j.drudis.2019.02.006
    Journal articles | 2017
    Hui A; Bajgrowicz-Cieslak M; Phan CM; Jones L, 2017, 'In vitro release of two anti-muscarinic drugs from soft contact lenses', Clinical Ophthalmology, 11, pp. 1657 - 1665, http://dx.doi.org/10.2147/OPTH.S141404
    Journal articles | 2017
    Hui A, 2017, 'Contact lenses for ophthalmic drug delivery', Clinical and Experimental Optometry, 100, pp. 494 - 512, http://dx.doi.org/10.1111/cxo.12592
    Journal articles | 2016
    Hui A; Willcox M, 2016, 'In vivo studies evaluating the use of contact lenses for drug delivery', Optometry and Vision Science, 93, pp. 367 - 376, http://dx.doi.org/10.1097/OPX.0000000000000809
    Journal articles | 2014
    Hui A; Willcox M; Jones L, 2014, 'In vitro and in vivo evaluation of novel ciprofloxacin-releasing silicone hydrogel contact lenses', Investigative Ophthalmology and Visual Science, 55, pp. 4896 - 4904, http://dx.doi.org/10.1167/iovs.14-14855
    Journal articles | 2012
    Hui A; Sheardown H; Jones L, 2012, 'Acetic and Acrylic Acid Molecular Imprinted Model Silicone Hydrogel Materials for Ciprofloxacin-hcl Delivery', Materials, 5, pp. 85 - 107, http://dx.doi.org/10.3390/ma5010085
    Journal articles | 2012
    Nguyen D; Hui A; Weeks A; Heynen M; Joyce E; Sheardown H; Jones L, 2012, 'Release of Ciprofloxacin-HCl and Dexamethasone Phosphate by Hyaluronic Acid Containing Silicone Polymers.', Materials (Basel), 5, pp. 684 - 698, http://dx.doi.org/10.3390/ma5040684
    Journal articles | 2012
    Soluri A; Hui A; Jones L, 2012, 'Delivery of ketotifen fumarate by commercial contact lens materials', Optometry and Vision Science, 89, pp. 1140 - 1149, http://dx.doi.org/10.1097/OPX.0b013e3182639dc8
    Journal articles | 2009
    Boone A; Hui A; Jones L, 2009, 'Uptake and release of dexamethasone phosphate from silicone hydrogel and group I, II, and IV hydrogel contact lenses', Eye and Contact Lens, 35, pp. 260 - 267, http://dx.doi.org/10.1097/ICL.0b013e3181b26c49
    Journal articles | 2008
    Hui A; Boone A; Jones L, 2008, 'Uptake and release of ciprofloxacin-HCl from conventional and silicone hydrogel contact lens materials.', Eye & contact lens, 34, pp. 266 - 271, http://dx.doi.org/10.1097/icl.0b013e3181812ba2
  • Conference Papers | 2022
    Sara M; Alex H; Chen R; Kumar N; Rajesh K; Kumar Mishara SK; Barron A; Yasir MUHAMMAD; Willcox M; Yasir M, 2022, 'Antimicrobial activity of peptoids against clinical pathogens.', in Antimicrobial activity of peptoids against clinical pathogens., USA, presented at peptoidsummit2022, USA, 11 August 2022 - 12 August 2022
    Conference Abstracts | 2021
    Sara M; Kuppusamy R; Afzal M; Khan M; Yasir M; Kalaiselvan P; Hui A; Kumar N; Willcox M, 2021, 'Synergistic activity of a peptide mimic with quinolones and cephalosporins against Staphylococcus aureus', in INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ASSOC RESEARCH VISION OPHTHALMOLOGY INC, Vol. 62, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000690760500400&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2014
    Hui A; Jones LW, 2014, 'Material Properties of Antibiotic Releasing Contact Lenses', in Material Properties of Antibiotic Releasing Contact Lenses, Association for Research in Vision and Ophthalmology, Orlando, Florida, presented at Association for Research in Vision and Ophthalmology, Orlando, Florida, 03 May 2014 - 08 May 2014
    Conference Papers | 2014
    Hui A; Willcox MDP; Jones LW, 2014, 'Material Properties and antimicrobial efficacy of novel antibacterial silicone hydrogel contact lenses.', Birmingham, United Kingdom, presented at BCLA Clinical Conference and Exhibition, Birmingham, United Kingdom, 06 June 2014 - 11 June 2014
    Theses / Dissertations | 2014
    Hui A, 2014, Contact Lenses for Ciprofloxacin Drug Delivery, University of Waterloo, University of Waterloo
    Conference Papers | 2013
    Hui A; Jones LW, 2013, 'Release of ciprofloxacin and dexamethasone from commercial contact lens materials', in Release of ciprofloxacin and dexamethasone from commercial contact lens materials, BCLA Clinical Conference and Exhibition, Manchester, UK, presented at BCLA Clinical Conference and Exhibition, Manchester, UK, 06 June 2013 - 09 June 2013
    Conference Papers | 2013
    Hui A; Jones LW, 2013, 'Uptake and Release of ciprofloxacin and dexamethasone from commercial contact lens materials', in Uptake and Release of ciprofloxacin and dexamethasone from commercial contact lens materials, Association for Research in Vision and Ophthalmology, Seattle, Washington, presented at Association for Research in Vision and Ophthalmology, Seattle, Washington, 05 May 2013 - 09 May 2013
    Conference Papers | 2013
    Hui A; Willcox MDP; Jones LW, 2013, 'In vitro evaluation of antimicrobial activity of novel ciprofloxacin releasing silicone hydrogels', in In vitro evaluation of antimicrobial activity of novel ciprofloxacin releasing silicone hydrogels, American Academy of Optometry, Seattle, Washington, presented at American Academy of Optometry, Seattle, Washington, 22 October 2013 - 26 October 2013
    Conference Papers | 2012
    Hui A; Soluri A; Jones LW, 2012, 'Ocular Delivery of Ketotifen Fumarate by Silicone Hydrogel and Conventional Hydrogel Contact Lens Materials', in Ocular Delivery of Ketotifen Fumarate by Silicone Hydrogel and Conventional Hydrogel Contact Lens Materials, Association for Research in Vision and Ophthalmology, Fort Lauderdale, FL, presented at Association for Research in Vision and Ophthalmology, Fort Lauderdale, FL, 06 May 2012 - 10 May 2012
    Conference Papers | 2011
    Hui A; Sheardown H; Jones LW, 2011, 'Molecular Imprinted Silicone Hydrogels for Ciprofloxacin Drug Delivery', in Molecular Imprinted Silicone Hydrogels for Ciprofloxacin Drug Delivery, American Academy of Optometry, Boston, MA, presented at American Academy of Optometry, Boston, MA, 11 October 2011 - 15 October 2011
    Conference Papers | 2011
    Hui A; Weeks AK; Sheardown H; Jones LW, 2011, 'Novel Silicone Hydrogel Materials for Ciprofloxacin Drug Delivery', in Novel Silicone Hydrogel Materials for Ciprofloxacin Drug Delivery, Association for Research in Vision and Ophthalmology, Fort Lauderdale, FL, presented at Association for Research in Vision and Ophthalmology, Fort Lauderdale, FL, 01 May 2011 - 05 May 2011

  • Vice-Chacellor's Award for Teaching Excellence - Rising Star and Early Career - UNSW - 2018
  • Faculty of Science Award for Excellent Early Teachers - UNSW - 2018
  • W.B Pearson Medal, Faculty of Science Graduate Office. University of Waterloo - 2015
  • Da Vinci Award - British Contact Lens Association - 2014
  • Desmond Fonn Contact Lens Research Award - School of Optometry & Vision Science - University of Waterloo - 2013
  • Endeavour Research Fellowship - Government of Australia - 2012
  • William C. Ezell Fellow - American Optometric Foundation, American Academy of Optometry - 2011, 2012
  • Natural Science and Engineering Research Council of Canada (NSERC) Alexander Graham Bell Canada Graduate Scholarship - 2010-2014
  • Carl Zeiss Vision Fellow - American Optometric Foundation, American Academy of Optometry - 2009

  • Contact Lenses
  • Ocular Drug Delivery
  • Ocular Pharmaceuticals
  • Myopia Control
  • Pathogenesis of Ocular Disease
  • Microbial Keratitis
  • Biomaterials