Drug Discovery |
![Waters Group: Regeneration and Stem cell Translational Research Waters Group: Regeneration and Stem cell Translational Research](/content/dam/images/medicine-health/biomedical-sciences/research/2024-07-research-themes-groups/2024-07-waters-group-regeneration-and-stem-cell-translational-research.cropimg.width=335.crop=video.jpg)
My team has developed an Australian national biobank of stem-cell-derived airway and gut organoids, and has built a platform for high-throughput functional therapy-testing on patients organoids.
Current projects
- Creation of patient-derived organoids for drug testing
- Organoid models for infection biology.
- Organoid-guided drug discovery for airway diseases.
- Functional modification of airway stem cells ex vivo, prior to transplantation into the in vivo airways.
Highlighted publications
- https://www.sciencedirect.com/science/article/pii/S2589004221016801
- https://www.atsjournals.org/doi/epdf/10.1165/rcmb.2021-0337OC?role=tab
- https://www.sciencedirect.com/science/article/pii/S1569199320309516?via%3Dihub
- https://www.mdpi.com/1422-0067/24/7/6475
- https://www.nature.com/articles/s41467-023-41907-1
Our experts
Dr Shafagh Waters - Group Leader
(BSc, MSc (Disc.), PhD)
I am a Scientia senior lecturer at UNSW and an honorary senior scientist at Sydney Children’s Hospital. I lead an internationally recognised, translational research program that focusses primarily on adult-stem cell biology for disease modelling to transform how we treat rare diseases by advancing genotype-specific precision interventions.
Team members
- Katelin Allan
- Bala Umashankar
- Egi Kardia
- Hojjatollah Nazari
- Laura Fawcett
- Megan Frohlich
- Naz Ebrahimi
- Laura Nementzik
- Kelly Yu
- Ruthvik Gundapaneni
Associated academics
Research Theme