The Tina Trial is a clinical trial designed to see whether mirtazapine, an antidepressant medication, can help people reduce their use of methamphetamine (ice, crystal meth). Two previous small trials in the USA found that mirtazapine helped people to reduce their methamphetamine use and improved their mood. We want to find out whether mirtazapine can be used in routine clinical care in Australia.

The trial has been funded by the Medical Research Future Fund and is being conducted by researchers and clinicians across Australia and in the USA. Further information about the team can be found here.

The Tina Trial is now closed. It is anticipated that results will be available in late 2025.

Where can I get help for ice use?

A number of free and confidential support services are available for people experiencing problems with ice, as well as their family and friends. Call the National Alcohol and Other Drug Hotline on 1800 250 015 to be automatically directed to the Alcohol and Drug Information Service in your state or territory.

For emergency support, call Lifeline on 131 114 or dial '000' for ambulance or police.